2.3.1.177: 3,5-dihydroxybiphenyl synthase

This is an abbreviated version!
For detailed information about 3,5-dihydroxybiphenyl synthase, go to the full flat file.

Word Map on EC 2.3.1.177

2.3.1.177

biphenyls

phytoalexins

dibenzofurans

sorbus

apple

aucuparin

polyketide

pear

elicitor-treated

starter

elicitors

rosaceae

malus

maloideae

subtribe

benzoic

domestica

blight

pyrus

amylovora

benzophenone

pyrinae

inaequalis

4-hydroxylation

venturia

4-hydroxycoumarin

rootstock

dot-shaped

delicious

replant

rosaceous

dicoumarol

greenhouse-grown

n-acetylcysteamine

4-coumaroyl-coa

pyrifolia

scab-causing

benzoate-coa

rowan

scab

Reaction

3 malonyl-CoA +

= 4 CoA +

+ 4 CO2

Synonyms

biphenyl synthase, BIS, BIS1, BIS1 biphenyl synthase, BIS2, BIS3, BIS3 biphenyl synthase, BIS4, MdBIS1, MdBIS3, PcBIS1, PcBIS2

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.177 3,5-dihydroxybiphenyl synthase

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Results	in table
1	Activating Compound
13	AA Sequence
7	Cloned(Commentary)
2	Crystallization (Commentary)
19	Expression
51	General Information
2	Inhibitors
13	kcat/KM [mM/s]
24	KM Value [mM]
3	Localization
5	Molecular Weight [Da]
19	Natural Substrates/ Products (Substrates)
30	Organism
1	Pathway
4	PDB ID
6	pH Optimum
2	pI Value
5	Purification (Commentary)
1	Reaction
3	Reaction Type
26	Reference
11	Source Tissue
35	Substrates and Products (Substrate)
1	Subunits
37	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
13	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 2.3.1.177 - 3,5-dihydroxybiphenyl synthase

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malonyl-CoA:benzoyl-CoA malonyltransferase

A polyketide synthase that is involved in the production of the phytoalexin aucuparin. 2-Hydroxybenzoyl-CoA can also act as substrate but it leads to the derailment product 4-hydroxycoumarin (cf. EC 2.3.1.208, 4-hydroxycoumarin synthase) [2]. This enzyme uses the same starter substrate as EC 2.3.1.151, benzophenone synthase.