2.3.1.168: dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
This is an abbreviated version!
For detailed information about dihydrolipoyllysine-residue (2-methylpropanoyl)transferase, go to the full flat file.
Word Map on EC 2.3.1.168
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2.3.1.168
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branched-chain
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bcaas
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merits
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protein-restricted
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retinal
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urine
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metformin
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women
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maple
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l-glutamate
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syrup
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agriculture
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synthesis
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medicine
- 2.3.1.168
-
branched-chain
-
bcaas
-
merits
-
protein-restricted
- retinal
- urine
- metformin
- women
-
maple
- l-glutamate
- syrup
- agriculture
- synthesis
- medicine
Reaction
Synonyms
Bkd, BKDH, DBT, dihydrolipoamide branched chain transacylase, dihydrolipoyl transacetylase, DLD, E2, E2p, More
ECTree
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Reaction
Reaction on EC 2.3.1.168 - dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
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2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
random bi bi mechanism
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2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
His391 is involved in the catalytic reaction
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2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine
the active site is located in the inner core domain
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