2.3.1.168: dihydrolipoyllysine-residue (2-methylpropanoyl)transferase

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For detailed information about dihydrolipoyllysine-residue (2-methylpropanoyl)transferase, go to the full flat file.

Reaction

Synonyms

Bkd, BKDH, DBT, dihydrolipoamide branched chain transacylase, dihydrolipoyl transacetylase, DLD, E2, E2p, More

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.168 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase

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Results	in table
174	AA Sequence
3	Application
13	Cloned(Commentary)
4	General Information
6	Inhibitors
6	KM Value [mM]
7	Localization
7	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
36	Organism
5	Pathway
41	PDB ID
1	pH Optimum
3	Protein Variants
8	Purification (Commentary)
4	Reaction
1	Reaction Type
34	Reference
4	Renatured (Commentary)
13	Source Tissue
5	Specific Activity [micromol/min/mg]
49	Substrates and Products (Substrate)
24	Subunits
34	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

Engineering

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Engineering on EC 2.3.1.168 - dihydrolipoyllysine-residue (2-methylpropanoyl)transferase

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PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

H391N

Bos taurus

-

enzymatically inactive

644842

H391Q

Bos taurus

-

enzymatically inactive

644842

F214C

Homo sapiens

P11182

natural splicing mutant from WG-34 cells, related to the maple syrup urine disease, phenotype of homo- and heterozygous mutations in humans

644842