2.3.1.161: lovastatin nonaketide synthase

This is an abbreviated version, for detailed information about lovastatin nonaketide synthase, go to the full flat file.

Reaction

9 malonyl-CoA + 11 NADPH + 10 H+ +

S-adenosyl-L-methionine
+
holo-[lovastatin nonaketide synthase]
=
dihydromonacolin L-[lovastatin nonaketide synthase]
+ 9 CoA + 9 CO2 + 11 NADP+ +
S-adenosyl-L-homocysteine
+ 6 H2O

Synonyms

LNKS, lovastatin nonaketide synthase, LovB, synthase, lovastatin nonaketide

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.161 lovastatin nonaketide synthase