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2.3.1.161: lovastatin nonaketide synthase

This is an abbreviated version!
For detailed information about lovastatin nonaketide synthase, go to the full flat file.

Word Map on EC 2.3.1.161

Reaction

9 malonyl-CoA + 11 NADPH + 10 H+ +

S-adenosyl-L-methionine
+
holo-[lovastatin nonaketide synthase]
=
dihydromonacolin L-[lovastatin nonaketide synthase]
 + 9 CoA + 9 CO2 + 11 NADP+ +
S-adenosyl-L-homocysteine
 + 6 H2O

Synonyms

LNKS, lovastatin nonaketide synthase, LovB, synthase, lovastatin nonaketide

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.161 lovastatin nonaketide synthase

Sequence

topprint

Sequence on EC 2.3.1.161 - lovastatin nonaketide synthase

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
LOVB_ASPTE
3038
0
335005
Swiss-Prot
other Location (Reliability: 2)
LOVB_ASPTN
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
3038
0
335023
Swiss-Prot
other Location (Reliability: 2)
LOVC_ASPTE
363
0
39511
Swiss-Prot
other Location (Reliability: 2)
LOVC_ASPTN
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
363
0
39442
Swiss-Prot
other Location (Reliability: 2)
MOKA_MONPI
3075
0
338037
Swiss-Prot
other Location (Reliability: 5)
B8MLL4_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2434
0
267301
TrEMBL
other Location (Reliability: 2)
B8MJ47_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2574
0
283293
TrEMBL
other Location (Reliability: 1)
B8MM59_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2528
0
277252
TrEMBL
other Location (Reliability: 2)
A0A0F4YNJ2_TALEM
2507
0
275906
TrEMBL
other Location (Reliability: 3)
B8MKY6_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2570
0
280373
TrEMBL
other Location (Reliability: 2)
A0A0F4YWL7_TALEM
2441
0
268479
TrEMBL
other Location (Reliability: 3)
B9PYE4_TOXGV
Toxoplasma gondii (strain ATCC 50861 / VEG)
10021
0
1093469
TrEMBL
other Location (Reliability: 4)
A0A125YWR9_TOXGM
Toxoplasma gondii (strain ATCC 50611 / Me49)
10021
0
1093469
TrEMBL
other Location (Reliability: 4)
A0A425HS93_TOXGO
4935
0
537026
TrEMBL
other Location (Reliability: 4)
A0A1S8AAC1_ROSNE
287
0
30835
TrEMBL
other Location (Reliability: 1)
B8MMZ2_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
944
0
104780
TrEMBL
other Location (Reliability: 2)
A0A3R8B0H5_TOXGO
3206
0
351058
TrEMBL
other Location (Reliability: 2)
A0A0F4Z407_TALEM
2645
0
290259
TrEMBL
other Location (Reliability: 1)
A0A086PSR3_TOXGO
4874
0
530255
TrEMBL
other Location (Reliability: 4)
A0A086JT50_TOXGO
4874
0
530301
TrEMBL
other Location (Reliability: 4)
B8MSF8_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2621
0
292309
TrEMBL
other Location (Reliability: 1)
A0A086QNR6_TOXGO
3127
0
342267
TrEMBL
other Location (Reliability: 1)
B8M9X6_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2388
0
259340
TrEMBL
other Location (Reliability: 2)
A0A1S8A8I9_ROSNE
372
0
40054
TrEMBL
Mitochondrion (Reliability: 3)
A0A0B6XAG6_XENBV
1089
0
122954
TrEMBL
-
A0A0F8B1C0_CERFI
1215
0
132247
TrEMBL
other Location (Reliability: 2)
A0A139XLM1_TOXGO
4958
0
539630
TrEMBL
other Location (Reliability: 4)
A0A086JYW5_TOXGO
4402
0
479141
TrEMBL
other Location (Reliability: 2)
B8M7V1_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2347
0
254045
TrEMBL
other Location (Reliability: 1)
A0A084GE65_PSEDA
2671
0
291005
TrEMBL
other Location (Reliability: 1)
A0A086LSF6_TOXGO
8102
0
884254
TrEMBL
other Location (Reliability: 3)
B8MSM2_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2368
0
257448
TrEMBL
other Location (Reliability: 1)
B8M0G9_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2432
0
264836
TrEMBL
other Location (Reliability: 3)
A0A0F4YEG7_TALEM
2638
0
291086
TrEMBL
other Location (Reliability: 1)
A0A2G8XS11_TOXGO
2195
1
239077
TrEMBL
Secretory Pathway (Reliability: 4)
B8M2A8_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
3725
0
413131
TrEMBL
other Location (Reliability: 1)
A0A125YWR8_TOXGG
Toxoplasma gondii (strain ATCC 50853 / GT1)
10021
0
1093469
TrEMBL
other Location (Reliability: 4)
K9V189_9CYAN
1967
0
222617
TrEMBL
-
A0A086KQL2_TOXGO
4874
0
530301
TrEMBL
other Location (Reliability: 4)
A0A383RRD8_9PSED
266
0
28963
TrEMBL
-
B8MV59_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2521
0
274036
TrEMBL
other Location (Reliability: 1)
B8MPC7_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
3928
0
433762
TrEMBL
other Location (Reliability: 2)
A0A2G8XS22_TOXGO
3330
0
364582
TrEMBL
other Location (Reliability: 1)
A0A086JT20_TOXGO
3127
0
342267
TrEMBL
other Location (Reliability: 1)
B8MFT5_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2436
0
268706
TrEMBL
other Location (Reliability: 2)
B8MP12_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2652
0
293187
TrEMBL
other Location (Reliability: 2)
A0A086PST4_TOXGO
3206
0
351147
TrEMBL
other Location (Reliability: 2)
A0A0N1G602_9ACTN
1519
0
166318
TrEMBL
-
B8MQ32_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2493
0
274764
TrEMBL
other Location (Reliability: 2)
G0PZX9_9ACTN
1988
0
214932
TrEMBL
-
A0A1S8A5D8_ROSNE
146
0
16604
TrEMBL
other Location (Reliability: 3)
A0A086QNT2_TOXGO
4874
0
530301
TrEMBL
other Location (Reliability: 4)
B8MPF4_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2515
0
275859
TrEMBL
other Location (Reliability: 2)
A0A086KQG0_TOXGO
3127
0
342267
TrEMBL
other Location (Reliability: 1)
B8MEL0_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2900
0
319164
TrEMBL
other Location (Reliability: 2)
B8MEK8_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2289
0
251996
TrEMBL
other Location (Reliability: 2)
A0A139XLM6_TOXGO
3311
0
362462
TrEMBL
other Location (Reliability: 3)
A0A2G8XT12_TOXGO
2629
0
284960
TrEMBL
other Location (Reliability: 2)
A0A086JYV0_TOXGO
3288
0
360081
TrEMBL
other Location (Reliability: 3)
B8MPM4_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
3968
0
439115
TrEMBL
other Location (Reliability: 2)
B8LWY1_TALSN
Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)
2262
0
248927
TrEMBL
other Location (Reliability: 2)
A0A0F4YYJ7_TALEM
2439
0
265318
TrEMBL
other Location (Reliability: 2)