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2.3.1.157: glucosamine-1-phosphate N-acetyltransferase

This is an abbreviated version!
For detailed information about glucosamine-1-phosphate N-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.157

Reaction

acetyl-CoA
+
alpha-D-glucosamine 1-phosphate
=
CoA
+
N-acetyl-alpha-D-glucosamine 1-phosphate

Synonyms

amino-sugar-1-P AcTase, amino-sugar-1-phosphate acetyltransferase, bifunctional GlmU protein, bifunctional N-acetyltransferase/uridylyltransferase, bifunctional protein GlmU, bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase, galactosamine-1-phosphate acetyltransferase, GalN-1-P AcTase, GlcN-1-P acetyltransferase, GlcN-1-P AcTase, GlcNAc-1-P uridyltransferase, GlmU, GlmU acetyltransferase, GlmU enzyme, GlmU uridyltransferase, glucosamine 1-phosphate N-acetyltransferase/N-acetylglucosamine-1-phosphate uridyltransferase, glucosamine-1-phosphate acetyltransferase, glucosamine-1-phosphate acetyltransferase/N-acetylglucosamine-1-phosphate uridyltransferase, More, MtbGlmU, MtGlmU, N-acetylglucosamine-1-phosphate pyrophosphorylase, N-acetylglucosamine-1-phosphate uridyltransferase, N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase, N-acetylglucosamine-1-phosphate-uridylyltransferase/glucosamine-1-phosphate-acetyltransferase, Rv1018c, Rxn-1, ST0452, ST0452 protein, STK_04520, UDP-GlcNAc pyrophosphorylase, UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.157 glucosamine-1-phosphate N-acetyltransferase

Specific Activity

Specific Activity on EC 2.3.1.157 - glucosamine-1-phosphate N-acetyltransferase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.004
-
mutant JM83(pFP3-Tr331), acetyltransferase activity
0.014
-
mutant JM83(pTrcHis30), uridyltransferase activity
0.11
-
mutant JM83(pTrcHis30), acetyltransferase activity
0.12
-
mutant JM83(pFP3-Tr331), uridyltransferase activity
0.35
pH 7.5, 80°C, mutant enzyme H308A
1131
alpha-D-glucosamine 1-phosphate aubstrate, pH 7.5, 80°C, recombinant mutant D011 protein
15.1
-
GlcNAc-1-P uridyltransferase activity
2.2
-
GlcN-1-P acetyltransferase activity
2.85
-
mutant JM83(pFP3-Tr331) + IPTG, uridyltransferase activity
23.1
pH 7.5, 80°C, mutant enzyme N331A
29.6
alpha-D-galactosamine 1-phosphate aubstrate, pH 7.5, 80°C, recombinant mutant D011 protein
3 - 8
alpha-D-galactosamine 1-phosphate substrate, pH 7.5, 80°C, recombinant mutant D005 protein
323.5
alpha-D-glucosamine 1-phosphate substrate, pH 7.5, 80°C, recombinant mutant D005 protein
47.6
alpha-D-galactosamine 1-phosphate aubstrate, pH 7.5, 80°C, recombinant wild-type ST0452 protein
50
pH 7.5, 80°C, wild-type enzyme enzyme
59.2
pH 7.5, 80°C, mutant enzyme Y311A
67.4
alpha-D-glucosamine 1-phosphate substrate, pH 7.5, 80°C, recombinant wild-type ST0452 protein
68.9
pH 7.5, 80°C, mutant enzyme K337A
73.5
pH 7.5, 80°C, mutant enzyme K340A
75.34
pH 7.5, 80°C, substrates: acetyl-CoA + alpha-D-glucosamine 1-phosphate