2.2.1.9: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase

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For detailed information about 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase, go to the full flat file.

Reaction

Synonyms

(1R,2S,5S,6S)-2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, (1R,2S,5S,6S)-2-succinyl-5-enolpyruvyl-6-hydroxycyclohex-3-ene-1-carboxylate synthase, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic acid synthase, EC 2.5.1.64, EcMenD, MenD, Rv0555, SEPHCHC synthase, SHCHC synthase

ECTree

     2 Transferases

         2.2 Transferring aldehyde or ketonic groups

             2.2.1 Transketolases and transaldolases

                2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase

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Results	in table
1	Activating Compound
13334	AA Sequence
1	CAS Registry Number
7	Cloned(Commentary)
10	Cofactor
8	Crystallization (Commentary)
6	General Information
3	General Stability
3	IC50 Value
5	Inhibitors
37	kcat/KM [mM/s]
3	Ki Value [mM]
44	KM Value [mM]
7	Metals/Ions
3	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
207	Organism
6	Pathway
153	PDB ID
3	pH Optimum
34	Protein Variants
8	Purification (Commentary)
4	Reaction
1	Reaction Type
17	Reference
1	Storage Stability
43	Substrates and Products (Substrate)
7	Subunits
41	Synonyms
1	Systematic Name
1	Temperature Stability [°C]
41	Turnover Number [1/s]

Temperature Stability

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Temperature Stability on EC 2.2.1.9 - 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase

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TEMPERATURE STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

additional information

Escherichia coli K-12

P17109

melting temperature 53°C, melting temperature 57.3°C of protein complex with thiamin diphosphate, melting temperature 54°C of protein complex with 2-oxoglutarate, melting temperature 54.5°C of protein complex with FAD

702035