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2.1.1.309: 18S rRNA (guanine1575-N7)-methyltransferase

This is an abbreviated version!
For detailed information about 18S rRNA (guanine1575-N7)-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.309

Reaction

S-adenosyl-L-methionine
+
guanine1575 in 18S rRNA
=
S-adenosyl-L-homocysteine
+
N7-methylguanine1575 in 18S rRNA

Synonyms

18S rRNA methyltransferase, BUD23, rRNA methyltransferase Bud23, WBSCR22, WBSCR22-TRMT112

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.309 18S rRNA (guanine1575-N7)-methyltransferase

Disease

Disease on EC 2.1.1.309 - 18S rRNA (guanine1575-N7)-methyltransferase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Breast Neoplasms
The Human WBSCR22 Protein Is Involved in the Biogenesis of the 40S Ribosomal Subunits in Mammalian Cells.
Cardiomyopathies
Cardiac mitochondrial function depends on BUD23 mediated ribosome programming.
Colorectal Neoplasms
Natural killer cells inhibit oxaliplatin-resistant colorectal cancer by repressing WBSCR22 via upregulating microRNA-146b-5p.
WBSCR22 Competes with Long Non-coding RNA Linc00346 for miR-509-5p Binding Site to Regulate Cancer Stem Cell Phenotypes of Colorectal Cancer.
WBSCR22 confers oxaliplatin resistance in human colorectal cancer.
Glioma
WBSCR22 confers cell survival and predicts poor prognosis in glioma.
Multiple Myeloma
Identification of molecular vulnerabilities in human multiple myeloma cells by RNA interference lethality screening of the druggable genome.
Neoplasm Metastasis
WBSCR22 confers cell survival and predicts poor prognosis in glioma.
WBSCR22 confers oxaliplatin resistance in human colorectal cancer.
Neoplasms
The Human WBSCR22 Protein Is Involved in the Biogenesis of the 40S Ribosomal Subunits in Mammalian Cells.
WBSCR22 Competes with Long Non-coding RNA Linc00346 for miR-509-5p Binding Site to Regulate Cancer Stem Cell Phenotypes of Colorectal Cancer.
WBSCR22 confers cell survival and predicts poor prognosis in glioma.
WBSCR22 confers oxaliplatin resistance in human colorectal cancer.
Williams Syndrome
Characterization of two novel genes, WBSCR20 and WBSCR22, deleted in Williams-Beuren syndrome.