2.1.1.237: mycinamicin III 3''-O-methyltransferase

This is an abbreviated version!
For detailed information about mycinamicin III 3''-O-methyltransferase, go to the full flat file.

Reaction

Synonyms

MycF

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.237 mycinamicin III 3''-O-methyltransferase

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Results	in table
39	AA Sequence
1	Application
1	Cloned(Commentary)
1	Cofactor
1	Crystallization (Commentary)
6	General Information
1	Inhibitors
1	kcat/KM [mM/s]
1	KM Value [mM]
6	Metals/Ions
1	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
5	Organism
4	Pathway
20	PDB ID
1	pH Optimum
1	Protein Variants
1	Purification (Commentary)
1	Reaction
5	Reference
4	Substrates and Products (Substrate)
1	Subunits
5	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 2.1.1.237 - mycinamicin III 3''-O-methyltransferase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

S-adenosyl-L-methionine + mycinamicin III

S-adenosyl-L-homocysteine + mycinamicin IV

3 entries

S-adenosyl-L-methionine + mycinamicin III

S-adenosyl-L-homocysteine + mycinamicin IV

Micromonospora griseorubida

-

-

715054

-

-

?

S-adenosyl-L-methionine + mycinamicin III

S-adenosyl-L-homocysteine + mycinamicin IV

Micromonospora griseorubida

-

the enzyme is involved in the biosynthesis of mycinamicin macrolide antibiotics

714732, 715054

-

-

?

S-adenosyl-L-methionine + mycinamicin III

S-adenosyl-L-homocysteine + mycinamicin IV

Micromonospora griseorubida

-

methylation of the C3''-OH of javose. Mycf possesses high substrate specificity. MycE is methylating mycinamycin VI

714732

-

-

?