2.1.1.237: mycinamicin III 3''-O-methyltransferase
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For detailed information about mycinamicin III 3''-O-methyltransferase, go to the full flat file.
Reaction
Synonyms
MycF
ECTree
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Engineering
Engineering on EC 2.1.1.237 - mycinamicin III 3''-O-methyltransferase
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additional information
a single amino acid substitution relaxes the 2'-methoxy specificity but retains regiospecificity. The engineered variant produces a new mycinamicin analogue, demonstrating the utility of structural information to facilitate bioengineering approaches for the chemoenzymatic synthesis of complex small molecules containing modified sugars