2.1.1.190: 23S rRNA (uracil1939-C5)-methyltransferase This is an abbreviated version! For detailed information about 23S rRNA (uracil1939-C5)-methyltransferase, go to the full flat file .
Reaction
S-adenosyl-L-methionine +
uracil1939 in 23S rRNA =
S-adenosyl-L-homocysteine +
5-methyluracil1939 in 23S rRNA
Synonyms m5U methyltransferase, Mcap0476, RlmCD, RlmD, RlmFO, RNA m5U methyltransferase, RNA uridine methyltransferase A, RumA, SP 1029, SP_1029, YefA, YgcA
ECTree
Systematic Name
Systematic Name on EC 2.1.1.190 - 23S rRNA (uracil1939-C5)-methyltransferase
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S-adenosyl-L-methionine:23S rRNA (uracil1939-C5)-methyltransferase
The enzyme specifically methylates uracil1939 at C5 in 23S rRNA [1]. The enzyme contains an [4Fe-4S] cluster coordinated by four conserved cysteine residues [2].