2.1.1.174: 23S rRNA (guanine1835-N2)-methyltransferase This is an abbreviated version! For detailed information about 23S rRNA (guanine1835-N2)-methyltransferase, go to the full flat file .
Reaction
S-adenosyl-L-methionine +
guanine1835 in 23S rRNA =
S-adenosyl-L-homocysteine +
N2-methylguanine1835 in 23S rRNA
Synonyms 23S rRNA methyltransferase, EC 2.1.1.51, EC 2.1.1.52, m2G1835, N2-methyltransferase RlmG, ribosomal RNA large subunit methyltransferase G, RlmG, ygjO
ECTree
Systematic Name
Systematic Name on EC 2.1.1.174 - 23S rRNA (guanine1835-N2)-methyltransferase
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S-adenosyl-L-methionine:23S rRNA (guanine1835-N2)-methyltransferase
The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate [1]. The enzyme specifically methylates guanine1835 at N2 in 23S rRNA.