2.1.1.174: 23S rRNA (guanine1835-N2)-methyltransferase
This is an abbreviated version!
For detailed information about 23S rRNA (guanine1835-N2)-methyltransferase, go to the full flat file.
Reaction
Synonyms
23S rRNA methyltransferase, EC 2.1.1.51, EC 2.1.1.52, m2G1835, N2-methyltransferase RlmG, ribosomal RNA large subunit methyltransferase G, RlmG, ygjO
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 2.1.1.174 - 23S rRNA (guanine1835-N2)-methyltransferase
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REACTION DIAGRAM
S-adenosyl-L-methionine + guanine1835 in 23S rRNA
S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA
additional information
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molecular modeling of RlmG-AdoMet-rRNA complex
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S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA
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S-adenosyl-L-methionine + guanine1835 in 23S rRNA
S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA
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S-adenosyl-L-methionine + guanine1835 in 23S rRNA
S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA
the nucleotide m2G1835 is located in a functionally extremely important region of the ribosome, being located within intersubunit bridges of group B2
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S-adenosyl-L-methionine + guanine1835 in 23S rRNA
S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA
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m2G1835 is located at ribosomal subunits 50S and 30S interface
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