Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
3 S-adenosyl-L-methionine + [chloroplastic fructose 1,6-bisphosphate aldolase]-L-lysine
3 S-adenosyl-L-homocysteine + [chloroplastic fructose 1,6-bisphosphate aldolase]-N6,N6,N6-trimethyl-L-lysine
reaction of EC 2.1.1.259
-
-
?
3 S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate-carboxylase]-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate-carboxylase]-N6,N6,N6-trimethyl-L-lysine
-
-
-
?
S-adenosyl-L-homocysteine + [gamma-tocopherol methyltransferase]-L-lysine
S-adenosyl-L-homocysteine [gamma-tocopherol methyltransferase]-N6-methyl-L-lysine
-
-
-
-
?
S-adenosyl-L-methionine + histone L-lysine
S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine
S-adenosyl-L-methionine + L-Lys
S-adenosyl-L-homocysteine + methyl-L-Lys
-
-
-
?
S-adenosyl-L-methionine + methyl-L-Lys
S-adenosyl-L-homocysteine + dimethyl-L-Lys + trimethyl-L-Lys
about 2fold higher activity than with Lys
-
-
?
S-adenosyl-L-methionine + ribulose-1,5-bisphosphate carboxylase
?
-
ribulose-1,5-bisphosphate carboxylase from Spinacia sp.
-
-
?
S-adenosyl-L-methionine + [chloroplastic fructose 1,6-bisphosphate aldolase isoform 2]-L-lysine
S-adenosyl-L-homocysteine + [chloroplastic fructose 1,6-bisphosphate aldolase isoform 2]-N6-methyl-L-lysine
S-adenosyl-L-methionine + [chloroplastic fructose 1,6-bisphosphate aldolase isoform 3]-L-lysine
S-adenosyl-L-homocysteine + [chloroplastic fructose 1,6-bisphosphate aldolase isoform 3]-N6-methyl-L-lysine
S-adenosyl-L-methionine + [fructose-1,6-bisphosphate aldolase]-lysine
S-adenosyl-L-homocysteine + [fructose-1,6-bisphosphate aldolase]-N6-methyl-L-lysine
-
-
-
-
?
S-adenosyl-L-methionine + [gamma-tocopherol methyltransferase]-L-lysine
S-adenosyl-L-homocysteine + [gamma-tocopherol methyltransferase]-N6-methyl-L-lysine
-
-
-
-
?
S-adenosyl-L-methionine + [gamma-tocopherol methyltransferase]-lysine
S-adenosyl-L-homocysteine + [gamma-tocopherol methyltransferase]-N6-methyl-L-lysine
-
methylation is required for gamma-tocopherol methyltransferase activity
-
-
?
S-adenosyl-L-methionine + [large subunit of Rubisco]-L-lysine
S-adenosyl-L-homocysteine + [large subunit of Rubisco]-N6-methyl-L-lysine
-
methylation occurs at Lys-394
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate-carboxylase]-L-lysine
?
-
the enzyme catalyzes the posttranslational methylation of the epsilon-amino group of Lys-14 in the large subunit of Rubisco
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate-carboxylase]-L-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate-carboxylase]-N6-methyl-L-lysine
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate-carboxylase]-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate-carboxylase]-N6-methyl-L-lysine
additional information
?
-
S-adenosyl-L-methionine + histone L-lysine
S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine
-
-
-
?
S-adenosyl-L-methionine + histone L-lysine
S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine
-
-
-
?
S-adenosyl-L-methionine + [chloroplastic fructose 1,6-bisphosphate aldolase isoform 2]-L-lysine
S-adenosyl-L-homocysteine + [chloroplastic fructose 1,6-bisphosphate aldolase isoform 2]-N6-methyl-L-lysine
-
-
-
-
?
S-adenosyl-L-methionine + [chloroplastic fructose 1,6-bisphosphate aldolase isoform 2]-L-lysine
S-adenosyl-L-homocysteine + [chloroplastic fructose 1,6-bisphosphate aldolase isoform 2]-N6-methyl-L-lysine
-
-
-
-
?
S-adenosyl-L-methionine + [chloroplastic fructose 1,6-bisphosphate aldolase isoform 3]-L-lysine
S-adenosyl-L-homocysteine + [chloroplastic fructose 1,6-bisphosphate aldolase isoform 3]-N6-methyl-L-lysine
-
-
-
-
?
S-adenosyl-L-methionine + [chloroplastic fructose 1,6-bisphosphate aldolase isoform 3]-L-lysine
S-adenosyl-L-homocysteine + [chloroplastic fructose 1,6-bisphosphate aldolase isoform 3]-N6-methyl-L-lysine
-
-
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine
-
Rubisco LSMT utilizes a processive reaction mechanism to catalyse exclusively trimethylation of Lys14 without disassociation from Rubisco
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine
-
methylation of lysine 14 of the large subunit
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine
-
Rubisco LSMT utilizes a processive reaction mechanism to catalyse exclusively trimethylation of Lys14 without disassociation from Rubisco
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine
-
methylation of lysine 14 of the large subunit
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine
-
LSMT transfers one or two methyl groups to a single lysine
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine
-
LSMT transfers two methyl groups to a single lysine
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine
-
Rubisco LSMT utilizes a processive reaction mechanism to catalyse exclusively trimethylation of Lys14 without disassociation from Rubisco
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine
-
methylation of lysine 14 of the large subunit
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine
-
Rubisco from spinach or tobacco leaves. LSMT transfers one or two methyl groups to a single lysine
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine
-
Rubisco LSMT utilizes a processive reaction mechanism to catalyse exclusively trimethylation of Lys14 without disassociation from Rubisco
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine
-
methylation of lysine 14 of the large subunit
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate-carboxylase]-L-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate-carboxylase]-N6-methyl-L-lysine
-
-
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate-carboxylase]-L-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate-carboxylase]-N6-methyl-L-lysine
-
the enzyme does not distinguish between the enzyme form activated by Mg2+ and CO2 and the unactivated enzyme form
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate-carboxylase]-L-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate-carboxylase]-N6-methyl-L-lysine
-
inactive on ribulose-bisphosphate-carboxylases that contain trimethyllysyl residues at position 14 in the large subunit
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate-carboxylase]-L-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate-carboxylase]-N6-methyl-L-lysine
-
catalyzes methylation of the epsilon-amino group of Lys-14 in the large subunit of ribulose-bisphosphate-carboxylase from Spinacia oleracea
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate-carboxylase]-L-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate-carboxylase]-N6-methyl-L-lysine
-
-
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate-carboxylase]-L-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate-carboxylase]-N6-methyl-L-lysine
-
catalyzes methylation of the epsilon-amino group of Lys-14 in the large subunit of ribulose-bisphosphate-carboxylase from Spinacia oleracea
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate-carboxylase]-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate-carboxylase]-N6-methyl-L-lysine
-
-
-
?
S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate-carboxylase]-lysine
S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate-carboxylase]-N6-methyl-L-lysine
specifically methylates Lys14 of the large subunit of ribulose-1,5-bisphosphate-carboxylase
-
-
?
additional information
?
-
-
in Arabidopsis, the large subunit of Rubisco is not naturally methylated. LSMT-L is able to interact with unmethylated Rubisco, but the complex is catalytically unproductive
-
-
?
additional information
?
-
-
histone methylation has significant effects on heterochromatin formation and transcriptional regulation
-
-
?
additional information
?
-
-
LSMT has both mono-and di-methylation activities. Determination of free energy reaction profiles and transition state geometries using the crystal structure and on-the-fly ab initio QM/MM MD simulations in two simulation systems: LSMTAdoMet-Lys and LSMT-AdoMet-MeLys, which are enzyme-substrate complexes for mono- and di-methylation reactions in LSMT, method, overview. Methylation state specificity, overview
-
-
?
additional information
?
-
-
several chloroplast-localized proteins are potential protein substrates for Rubisco LSMT
-
-
?
additional information
?
-
bifunctional enzyme that catalyzes methylation of both the alpha-amino group of the small subunit of ribulose-1,5-bisphosphate-carboxylase
-
-
?
additional information
?
-
-
bifunctional enzyme that catalyzes methylation of both the alpha-amino group of the small subunit of ribulose-1,5-bisphosphate-carboxylase
-
-
?