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1.5.99.13: D-proline dehydrogenase

This is an abbreviated version!
For detailed information about D-proline dehydrogenase, go to the full flat file.

Reaction

D-proline
+
acceptor
=
1-pyrroline-2-carboxylate
 +
reduced acceptor

Synonyms

D-Pro dehydrogenase, D-Pro DH, D-proline dehydrogenase, dye-dependent proline dehydrogenase, dye-linked D-proline dehydrogenase, PDH

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.99 With unknown physiological acceptors
                1.5.99.13 D-proline dehydrogenase

Substrates Products

Substrates Products on EC 1.5.99.13 - D-proline dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
allo-4-hydroxy-D-proline + oxidized 2,6-dichloroindophenol + H2O
? + reduced 2,6-dichloroindophenol
show the reaction diagram
D-alanine + oxidized 2,6-dichloroindophenol + H2O
pyruvate + NH3 + reduced 2,6-dichloroindophenol
show the reaction diagram
D-arginine + oxidized 2,6-dichloroindophenol + H2O
2-oxo-5-guanidinopentanoate + NH3 + reduced 2,6-dichloroindophenol
show the reaction diagram
D-aspartate + oxidized 2,6-dichloroindophenol + H2O
oxaloacetate + NH3 + reduced 2,6-dichloroindophenol
show the reaction diagram
D-glutamate + oxidized 2,6-dichloroindophenol + H2O
2-oxo-glutarate + NH3 + reduced 2,6-dichloroindophenol
show the reaction diagram
23% of the activity with D-proline
-
-
?
D-histidine + oxidized 2,6-dichloroindophenol + H2O
3-(1H-imidazol-4-yl)-2-oxopropanoate + NH3 + reduced 2,6-dichloroindophenol
show the reaction diagram
D-isoleucine + oxidized 2,6-dichloroindophenol + H2O
3-methyl-2-oxopropanoate + NH3 + reduced 2,6-dichloroindophenol
show the reaction diagram
D-leucine + oxidized 2,6-dichloroindophenol + H2O
4-methyl-2-oxopentanoate + NH3 + reduced 2,6-dichloroindophenol
show the reaction diagram
D-phenylalanine + oxidized 2,6-dichloroindophenol + H2O
phenylpyruvate + NH3 + reduced 2,6-dichloroindophenol
show the reaction diagram
28% of the activity with D-proline
-
-
?
D-proline + 2,6-dichlorophenolindophenol
1-pyrroline-2-carboxylate + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
-
-
-
r
D-proline + oxidized 2,6-dichloroindophenol
DELTA1-pyrroline 2-carboxylate + reduced 2,6-dichloroindophenol
show the reaction diagram
D-proline + oxidized 2,6-dichlorophenolindophenol
DELTA1-pyrroline-2-carboxylate + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
-
-
-
-
?
D-proline + oxidized 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
DELTA1-pyrroline 2-carboxylate + reduced 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
show the reaction diagram
33% of the activity with oxidized 2,6-dichloroindophenol
-
-
?
D-proline + oxidized phenazine methosulfate
DELTA1-pyrroline 2-carboxylate + reduced phenazine methosulfate
show the reaction diagram
43% of the activity with oxidized 2,6-dichloroindophenol
-
-
?
D-serine + oxidized 2,6-dichloroindophenol + H2O
3-hydroxy-2-oxopropanoate + NH3 + reduced 2,6-dichloroindophenol
show the reaction diagram
13% of the activity with D-proline
-
-
?
D-threonine + oxidized 2,6-dichloroindophenol + H2O
3-hydroxy-2-oxobutanoate + NH3 + reduced 2,6-dichloroindophenol
show the reaction diagram
15% of the activity with D-proline
-
-
?
D-tryptophan + oxidized 2,6-dichloroindophenol + H2O
3-indole-2-oxopropanoate + NH3 + reduced 2,6-dichloroindophenol
show the reaction diagram
14% of the activity with D-proline
-
-
?
D-valine + oxidized 2,6-dichloroindophenol + H2O
2-oxoisopentanoate + NH3 + reduced 2,6-dichloroindophenol
show the reaction diagram
additional information
?
-