EC Number |
Protein Variants |
Reference |
---|
5.1.1.11 | C331A |
minor changes in activity or specificity |
703679 |
5.1.1.11 | C331L |
activity of GrsA is decreased to 26% |
703679 |
5.1.1.11 | C376S |
no changes in activity |
703679 |
5.1.1.11 | C473A |
no changes in activity |
703679 |
5.1.1.11 | C60F |
no changes in activity |
703679 |
5.1.1.11 | C60F/C331A/C376S/C473A |
named A-PCP(delta-4Cys), Km for L-Phe is increased by 2fold, while the kcat is reduced by 1.5fold |
703679 |
5.1.1.11 | D767S |
mutant enzyme is impaired in approach to D-Phe/L-Phe-S-4'phosphopantetheine equilibrium only for D-Phe to L-Phe direction |
649989 |
5.1.1.11 | E892A |
mutant enzyme is dramatically impaired in approach to D-Phe/L-Phe-S-4'phosphopantetheine equilibrium from either D-Phe or L-Phe |
649989 |
5.1.1.11 | E892A |
only slightly active with L-Phe, unimpaired reaction with D-Phe |
649989 |
5.1.1.11 | H753A |
only slightly active with L-Phe, unimpaired reaction with D-Phe |
649989 |