EC Number |
Protein Variants |
Reference |
---|
2.3.1.167 | more |
functional expression in Saccharomyces cerevisiae for reconstruction of taxoid biosynthesis |
672704 |
2.3.1.167 | D166A |
decrease of kcat/KM of 10-deacetylbaccatin III and acetyl CoA |
755829 |
2.3.1.167 | D34E |
decrease of kcat/KM of 10-deacetylbaccatin III and acetyl CoA |
755829 |
2.3.1.167 | D372E |
decrease of kcat/KM of 10-deacetylbaccatin III and acetyl CoA |
755829 |
2.3.1.167 | G376A |
decrease of kcat/KM of 10-deacetylbaccatin III and acetyl CoA |
755829 |
2.3.1.167 | H162A |
mutation results in complete loss of enzymatic activity, suggesting that the residue histidine at 162 is essential to DBAT activity |
755829 |
2.3.1.167 | R363A |
decrease of kcat/KM of 10-deacetylbaccatin III and acetyl CoA |
755829 |
2.3.1.167 | S31A |
decrease of kcat/KM of 10-deacetylbaccatin III and acetyl CoA |
755829 |
2.3.1.167 | D390H |
catalytic efficiency towards 10-deacetylbaccatin III and vinyl acetate is 96% of the wild-type value |
757640 |
2.3.1.167 | D390R |
catalytic efficiency towards 10-deacetylbaccatin III and vinyl acetate is improved by 2.3fold |
757640 |