EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.4.22.55 | Acrocephalosyndactylia |
11854168 |
Twist haploinsufficiency in Saethre-Chotzen syndrome induces calvarial osteoblast apoptosis due to increased TNFalpha expression and caspase-2 activation. |
causal interaction unassigned |
2 0 |
3.4.22.55 | Adenocarcinoma |
25010987 |
Attenuation of the ELAV1-like protein HuR sensitizes adenocarcinoma cells to the intrinsic apoptotic pathway by increasing the translation of caspase-2L. |
causal interaction ongoing research unassigned |
1 3 0 |
3.4.22.55 | Adenocarcinoma of Lung |
15941563 |
Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway. |
ongoing research therapeutic application unassigned |
4 2 0 |
3.4.22.55 | Adenocarcinoma of Lung |
18375382 |
c-Myc and caspase-2 are involved in activating Bax during cytotoxic drug-induced apoptosis. |
diagnostic usage ongoing research unassigned |
1 4 0 |
3.4.22.55 | Adenoma, Pleomorphic |
27981346 |
Altered expression of apoptosis-regulating miRNAs in salivary gland tumors suggests their involvement in salivary gland tumorigenesis. |
diagnostic usage ongoing research unassigned |
3 1 0 |
3.4.22.55 | Alzheimer Disease |
9507158 |
Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease. |
causal interaction therapeutic application unassigned |
2 1 0 |
3.4.22.55 | Alzheimer Disease |
10079193 |
Changes in caspase expression in Alzheimer's disease: comparison with development and aging. |
causal interaction diagnostic usage ongoing research unassigned |
1 3 2 0 |
3.4.22.55 | Alzheimer Disease |
23748737 |
Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice. |
causal interaction therapeutic application unassigned |
4 4 0 |
3.4.22.55 | Alzheimer Disease |
27901073 |
THD-Module Extractor: An Application for CEN Module Extraction and Interesting Gene Identification for Alzheimer's Disease. |
causal interaction unassigned |
4 0 |
3.4.22.55 | Alzheimer Disease |
31362787 |
A soluble tau fragment generated by caspase-2 is associated with dementia in Lewy body disease. |
causal interaction unassigned |
3 0 |