EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
    1.14.18.1 | -999 |
- |
more |
1-hydroxy-2-oxo-1-phenylhydrazine displays competitive inhibition at pH 6.8 and 5.8, all the other N-substituted N-nitrosohydroxylamines show a different type of inhibition at pH 6.8. and 5.8 |
688039 |
| 1.14.18.1 | -999 |
- |
more |
daedalin A also shows 1,1-diphenyl-2-picrylhydrazyl scavenging activity (IC50: 16.9 microM) and superoxide anion scavenging activity (IC50: 28.5 microM) |
685668 |
| 1.14.18.1 | -999 |
- |
more |
Ganoderma lucidum exhibits significant inhibition of tyrosinase activity, IC50 value 0.32 mg/ml |
689118 |
| 1.14.18.1 | -999 |
- |
more |
IC50 values for N-phenylurea, 1-(2,4-dimethoxyphenyl)-3-hydroxyurea, 1-(4-butoxyphenyl)-3-hydroxyurea, 3-(4-bromophenyl)-1-hydroxy-1-methylurea, 1-methoxy-3-phenylurea, 1-hydroxy-1-methyl-3-phenylurea, 1-hydroxy-1,3-dimethyl-3-phenylurea, 3-methoxy-1-methyl-1-phenylurea, 1-hydroxy-3-phenylthiourea, 1-methoxy-3-(4-nitrophenyl)thiourea are above 1 mM |
685604 |
| 1.14.18.1 | -999 |
- |
more |
IC50-value for petroleum ether: 8.09 mg/ml, IC50-value for crude ethanol phase (ECPE): 7.53 mg/ml, IC50-value for macroporus adsorption resin (FGRE): 4.80 mg/ml |
688037 |
| 1.14.18.1 | -999 |
- |
more |
IC50-values above 1 mM for artocarpin, cycloartocarpin, and cycloartocarpesin |
689064 |
| 1.14.18.1 | -999 |
- |
more |
methanolic and acetonic extracts of the stem bark of Sideroxylon inerme show significant inhibition of monophenolase activity (IC50 values of 63 microg/ml and 82 microg/ml). The methanolic extract also exhibits 37% reduction of melanin content at 6.2 microg/ml in melanocytes without being significantly toxic to the cells |
688064 |
| 1.14.18.1 | 0.0000167 |
- |
2-[2-methyl-5-(propan-2-yl)phenoxy]-2-oxoethyl (2E)-3-(2,4-dihydroxyphenyl)prop-2-enoate |
pH 6.8, 25°C |
746224 |
| 1.14.18.1 | 0.000075 |
- |
1-cyclopentyl-1-hydroxy-2-oxohydrazine |
at pH 5.8 |
688039 |
| 1.14.18.1 | 0.000086 |
- |
1-(propan-2-ylidene)thiosemicarbazide |
most potent inhibitor |
686532 |
