EC Number |
Turnover Number Minimum [1/s] |
Turnover Number Maximum [1/s] |
Substrate |
Reference |
---|
3.4.22.61 | 0.37 |
- |
acetyl-DEVD-7-amido-4-methylcoumarin |
pH 7.0 or pH 7.5 |
647424 |
3.4.22.61 | 0.65 |
- |
acetyl-IETD-7-amido-4-fluoromethylcoumarin |
cleaved caspase-8, 37°C, pH 7.4 |
663939 |
3.4.22.61 | 0.78 |
- |
acetyl-IETD-7-amido-4-fluoromethylcoumarin |
non-cleavable caspase-8 + 0.001 mM FLIP D297A, 37°C, pH 7.4, in the presence of 0.7 M sodium citrate |
663939 |
3.4.22.61 | 0.98 |
- |
acetyl-IETD-7-amido-4-fluoromethylcoumarin |
non-cleavable caspase-8 + 0.001 mM FLIP, 37°C, pH 7.4, in the presence of 0.7 M sodium citrate |
663939 |
3.4.22.61 | 1.25 |
- |
acetyl-IETD-7-amido-4-fluoromethylcoumarin |
cleaved caspase-8, 37°C, pH 7.4, in the presence of 0.7 M sodium citrate |
663939 |