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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.72more both isoforms Cca1 and Cca2 accept the complete sets of cytosolic and mitochondrial tRNAs at the individual developmental stages. Isoform Cca2 shows efficient binding to the substrates with a Kd of 2.3 microM and 1.7 microM for the in vitro transcript and the in vivo tRNA preparation, respectively. Isoform Cca1 shows almost no binding at any protein concentration Dictyostelium discoideum ? - -
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.72more enzyme accepts normal tRNA precursors as well as mitochondrial miniaturized hairpin-like tRNA molecules that lack D- as well as T-arms Romanomermis culicivorax ? - -
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.72a tRNA precursor + 2 CTP + ATP - Arabidopsis thaliana a tRNA with a 3'CCA end + 3 diphosphate - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.72a tRNA precursor + 2 CTP + ATP - Saccharolobus shibatae a tRNA with a 3'CCA end + 3 diphosphate - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.72a tRNA precursor + 2 CTP + ATP - Homo sapiens a tRNA with a 3' CCA end + 3 diphosphate - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.72a tRNA precursor + 2 CTP + ATP - Archaeoglobus fulgidus a tRNA with a 3' CCA end + 3 diphosphate - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.72a tRNA precursor + 2 CTP + ATP - Saccharomyces cerevisiae a tRNA with a 3' CCA end + 3 diphosphate - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.72a tRNA precursor + 2 CTP + ATP overall reaction Saccharolobus shibatae a tRNA with a 3' CCA end + 3 diphosphate - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.72a tRNA precursor + 2 CTP + ATP the 30-region of RNA is proofread, after two nucleotide additions, in the closed, active form of the complex at the AMP incorporation stage. This proofreading is a prerequisite for the maintenance of fidelity for complete CCA synthesis Archaeoglobus fulgidus a tRNA with a 3' CCA end + 3 diphosphate - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.72a tRNA precursor + 2 CTP + ATP one catalytic center is responsible for addition of both CTP and ATP. As the single active site catalyzes addition of each nucleotide, the growing 3'-end of the tRNA would progressively refold to create a binding pocket for addition of the next nucleotide Saccharolobus shibatae a tRNA with a 3' CCA end + 3 diphosphate - ?
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