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EC NUMBER 
COMMENTARY 
-
preliminary BRENDA-supplied EC number
preliminary BRENDA-supplied EC number
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
(1'S,5'S)-averufin biosynthesis
-
-
PWY-5954
(3R)-N-[(2S)-1-hydroxy-6-[(3R)-3-isocyanobutanamido]hexan-2-yl]-3-isocyanobutanamide biosynthesis
-
-
PWY-8320
(5Z)-dodecenoate biosynthesis I
-
-
PWY0-862
(5Z)-dodecenoate biosynthesis II
-
-
PWY-7858
(5Z)-icosenoate biosynthesis
-
-
PWY-5361
(9Z)-tricosene biosynthesis
-
-
PWY-7035
(aminomethyl)phosphonate degradation
-
-
PWY-7805
(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)
-
-
PWY-7216
(R)-cysteate degradation
-
-
PWY-6642
(S)-lactate fermentation to propanoate, acetate and hydrogen
-
-
PWY-8086
(S)-propane-1,2-diol degradation
-
-
PWY-7013
(S)-reticuline biosynthesis I
-
-
PWY-3581
1,3-propanediol biosynthesis (engineered)
-
-
PWY-7385
1,5-anhydrofructose degradation
-
-
PWY-6992
1-butanol autotrophic biosynthesis (engineered)
-
-
PWY-6886
15-epi-lipoxin biosynthesis
-
-
PWY66-393
1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)
-
-
PWY-6361
1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)
-
-
PWY-6362
1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)
-
-
PWY-4661
1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)
-
-
PWY-6372
1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)
-
-
PWY-6554
2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA
-
-
PWY-5652
2-arachidonoylglycerol biosynthesis
-
-
PWY-8052
2-deoxy-D-ribose degradation II
-
-
PWY-8058
2-methyl-branched fatty acid beta-oxidation
-
-
PWY-8181
2-methylpropene degradation
-
-
PWY-7778
2-oxoglutarate decarboxylation to succinyl-CoA
-
-
PWY-5084
24-epi-campesterol, fucosterol, and clionasterol biosynthesis (diatoms)
-
-
PWY-8238
3-(4-hydroxyphenyl)pyruvate biosynthesis
-
-
PWY-5886
3-hydroxypropanoate cycle
-
-
PWY-5743
3-hydroxypropanoate/4-hydroxybutanate cycle
-
-
PWY-5789
3-methylarginine biosynthesis
-
-
PWY-6511
3-methylbutanol biosynthesis (engineered)
-
-
PWY-6871
3-phosphoinositide biosynthesis
-
-
PWY-6352
3-phosphoinositide degradation
-
-
PWY-6368
4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis II
-
-
PWY-7282
4-aminobutanoate degradation I
-
-
PWY-6535
4-aminobutanoate degradation II
-
-
PWY-6537
4-aminobutanoate degradation III
-
-
PWY-6536
4-aminobutanoate degradation V
-
-
PWY-5022
4-hydroxy-2-nonenal detoxification
-
-
PWY-7112
4-hydroxybenzoate biosynthesis I (eukaryotes)
-
-
PWY-5754
4-oxopentanoate degradation
-
-
PWY-7948
5-oxo-L-proline metabolism
-
-
PWY-7942
6-gingerol analog biosynthesis (engineered)
-
-
PWY-6920
6-hydroxymethyl-dihydropterin diphosphate biosynthesis
-
-
6-hydroxymethyl-dihydropterin diphosphate biosynthesis I
-
-
PWY-6147
6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)
-
-
PWY-7852
7-(3-amino-3-carboxypropyl)-wyosine biosynthesis
-
-
PWY-7286
8-amino-7-oxononanoate biosynthesis I
-
-
PWY-6519
ABH and Lewis epitopes biosynthesis from type 1 precursor disaccharide
-
-
PWY-7832
ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide
-
-
PWY-7831
Ac/N-end rule pathway
-
-
PWY-7800
acetaldehyde biosynthesis I
-
-
PWY-6333
acetoacetate degradation (to acetyl CoA)
-
-
ACETOACETATE-DEG-PWY
acetone degradation I (to methylglyoxal)
-
-
PWY-5451
acetone degradation III (to propane-1,2-diol)
-
-
PWY-7466
acetyl-CoA fermentation to butanoate
-
-
PWY-5676
acetylene degradation (anaerobic)
-
-
P161-PWY
acrylonitrile degradation I
-
-
PWY-7308
acyl carrier protein activation
-
-
PWY-6012-1
acyl carrier protein metabolism
-
-
PWY-6012
acyl-CoA hydrolysis
-
-
PWY-5148
adenine and adenosine salvage I
-
-
P121-PWY
adenine and adenosine salvage III
-
-
PWY-6609
adenine and adenosine salvage V
-
-
PWY-6611
adenine and adenosine salvage VI
-
-
PWY-6619
adenine salvage
-
-
PWY-6610
adenosine 5'-phosphoramidate biosynthesis
-
-
PWY-6794
adenosine deoxyribonucleotides de novo biosynthesis I
-
-
PWY-7227
adenosine deoxyribonucleotides de novo biosynthesis II
-
-
PWY-7220
adenosine nucleotides degradation I
-
-
PWY-6596
adenosine nucleotides degradation II
-
-
SALVADEHYPOX-PWY
adenosine ribonucleotides de novo biosynthesis
-
-
PWY-7219
aerobic respiration I (cytochrome c)
-
-
PWY-3781
aerobic respiration II (cytochrome c) (yeast)
-
-
PWY-7279
aerobic respiration III (alternative oxidase pathway)
-
-
PWY-4302
alginate degradation
-
-
PWY-6986
all-trans-farnesol biosynthesis
-
-
PWY-6859
allantoin degradation to ureidoglycolate I (urea producing)
-
-
PWY-5697
alliin metabolism
-
-
PWY-5706
alpha-linolenate metabolites biosynthesis
-
-
PWY-8398
alpha-tomatine degradation
-
-
PWY18C3-5
Amaryllidacea alkaloids biosynthesis
-
-
PWY-7826
ammonia assimilation cycle I
-
-
PWY-6963
ammonia assimilation cycle II
-
-
PWY-6964
ammonia assimilation cycle III
-
-
AMMASSIM-PWY
ammonia oxidation II (anaerobic)
-
-
P303-PWY
amygdalin and prunasin degradation
-
-
PWY-6011
anaerobic energy metabolism (invertebrates, cytosol)
-
-
PWY-7383
anaerobic energy metabolism (invertebrates, mitochondrial)
-
-
PWY-7384
anandamide biosynthesis I
-
-
PWY-8051
anandamide biosynthesis II
-
-
PWY-8053
anandamide degradation
-
-
PWY6666-1
anandamide lipoxygenation
-
-
PWY-8056
arachidonate biosynthesis I (6-desaturase, lower eukaryotes)
-
-
PWY-5353
arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)
-
-
PWY-7601
arachidonate biosynthesis V (8-detaturase, mammals)
-
-
PWY-7725
arachidonate metabolites biosynthesis
-
-
PWY-8397
Arg/N-end rule pathway (eukaryotic)
-
-
PWY-7799
arsenic detoxification (mammals)
-
-
PWY-4202
arsenite to oxygen electron transfer
-
-
PWY-4521
arsenite to oxygen electron transfer (via azurin)
-
-
PWY-7429
aspirin triggered resolvin D biosynthesis
-
-
PWY66-395
aspirin triggered resolvin E biosynthesis
-
-
PWY66-394
ATP biosynthesis
-
-
PWY-7980
atromentin biosynthesis
-
-
PWY-7518
autoinducer AI-1 biosynthesis
-
-
PWY-6157
avenanthramide biosynthesis
-
-
PWY-8157
bacterial bioluminescence
-
-
PWY-7723
baicalein degradation (hydrogen peroxide detoxification)
-
-
PWY-7214
benzoate biosynthesis II (CoA-independent, non-beta-oxidative)
-
-
PWY-6444
beta-D-glucuronide and D-glucuronate degradation
-
-
PWY-7247
betanidin degradation
-
-
PWY-5461
Bifidobacterium shunt
-
-
P124-PWY
biosynthesis of Lewis epitopes (H. pylori)
-
-
PWY-7833
bisabolene biosynthesis (engineered)
-
-
PWY-7102
bryostatin biosynthesis
-
-
PWY-8047
bupropion degradation
-
-
PWY66-241
butanol and isobutanol biosynthesis (engineered)
-
-
PWY-7396
C20 prostanoid biosynthesis
-
-
PWY66-374
C25,25 CDP-archaeol biosynthesis
-
-
PWY-8365
C4 photosynthetic carbon assimilation cycle, NAD-ME type
-
-
PWY-7115
C4 photosynthetic carbon assimilation cycle, NADP-ME type
-
-
PWY-241
C4 photosynthetic carbon assimilation cycle, PEPCK type
-
-
PWY-7117
Calvin-Benson-Bassham cycle
-
-
CALVIN-PWY
camalexin biosynthesis
-
-
CAMALEXIN-SYN
canavanine biosynthesis
-
-
PWY-5
cannabinoid biosynthesis
-
-
PWY-5140
capsaicin biosynthesis
-
-
PWY-5710
cardenolide glucosides biosynthesis
-
-
PWY-6036
cellulose biosynthesis
-
-
PWY-1001
cellulose degradation II (fungi)
-
-
PWY-6788
ceramide and sphingolipid recycling and degradation (yeast)
-
-
PWY-7119
ceramide de novo biosynthesis
-
-
PWY3DJ-12
ceramide degradation (generic)
-
-
PWY-6483
ceramide degradation by alpha-oxidation
-
-
PWY66-388
chitin biosynthesis
-
-
PWY-6981
chitin deacetylation
-
-
PWY-7118
chitin degradation I (archaea)
-
-
PWY-6855
chitin degradation II (Vibrio)
-
-
PWY-6902
chitin degradation III (Serratia)
-
-
PWY-7822
chitin derivatives degradation
-
-
PWY-6906
chlorogenic acid biosynthesis I
-
-
PWY-6039
chlorogenic acid degradation
-
-
PWY-6781
cholesterol biosynthesis (algae, late side-chain reductase)
-
-
PWY-8191
cholesterol biosynthesis (diatoms)
-
-
PWY-8239
cholesterol biosynthesis (plants, early side-chain reductase)
-
-
PWY18C3-1
cholesterol biosynthesis II (via 24,25-dihydrolanosterol)
-
-
PWY66-3
choline biosynthesis III
-
-
PWY-3561
cinnamoyl-CoA biosynthesis
-
-
PWY-6457
CMP phosphorylation
-
-
PWY-7205
CO2 fixation into oxaloacetate (anaplerotic)
-
-
PWYQT-4429
coenzyme M biosynthesis II
-
-
PWY-6643
colanic acid building blocks biosynthesis
-
-
COLANSYN-PWY
complex N-linked glycan biosynthesis (plants)
-
-
PWY-7920
complex N-linked glycan biosynthesis (vertebrates)
-
-
PWY-7426
coumarin biosynthesis (via 2-coumarate)
-
-
PWY-5176
coumarins biosynthesis (engineered)
-
-
PWY-7398
creatine phosphate biosynthesis
-
-
PWY-6158
crotonate fermentation (to acetate and cyclohexane carboxylate)
-
-
PWY-7401
curcuminoid biosynthesis
-
-
PWY-6432
cutin biosynthesis
-
-
PWY-321
cyanate degradation
cycloartenol biosynthesis
-
-
PWY-8028
cytochrome c biogenesis (system I type)
-
-
PWY-8147
cytosolic NADPH production (yeast)
-
-
PWY-7268
D-arabinose degradation V
-
-
PWY-8334
D-galactose degradation I (Leloir pathway)
-
-
PWY-6317
D-galactose degradation IV
-
-
PWY-6693
D-galactose detoxification
-
-
PWY-3821
D-myo-inositol (1,3,4)-trisphosphate biosynthesis
-
-
PWY-6364
D-myo-inositol (1,4,5)-trisphosphate biosynthesis
-
-
PWY-6351
D-myo-inositol (1,4,5)-trisphosphate degradation
-
-
PWY-6363
D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis
-
-
PWY-6366
D-myo-inositol-5-phosphate metabolism
-
-
PWY-6367
D-sorbitol biosynthesis I
-
-
PWY-5054
D-xylose degradation to ethylene glycol (engineered)
-
-
PWY-7178
degradation of aromatic, nitrogen containing compounds
-
-
detoxification of reactive carbonyls in chloroplasts
-
-
PWY-6786
di-homo-gamma-linolenate metabolites biosynthesis
-
-
PWY-8396
di-myo-inositol phosphate biosynthesis
-
-
PWY-6664
diacylglycerol and triacylglycerol biosynthesis
-
-
TRIGLSYN-PWY
diethylphosphate degradation
-
-
PWY-5491
docosahexaenoate metabolites biosynthesis
-
-
PWY-8400
dopamine degradation
-
-
PWY6666-2
drosopterin and aurodrosopterin biosynthesis
-
-
PWY-7442
dTMP de novo biosynthesis (mitochondrial)
-
-
PWY66-385
dZTP biosynthesis
-
-
PWY-8289
enterobactin biosynthesis
-
-
ENTBACSYN-PWY
Entner-Doudoroff pathway I
-
-
PWY-8004
Entner-Doudoroff pathway II (non-phosphorylative)
-
-
NPGLUCAT-PWY
Entner-Doudoroff pathway III (semi-phosphorylative)
-
-
PWY-2221
ephedrine biosynthesis
-
-
PWY-5883
ergosterol biosynthesis II
-
-
PWY-7154
ergothioneine biosynthesis I (bacteria)
-
-
PWY-7255
erythritol biosynthesis I
-
-
PWY-8372
erythritol biosynthesis II
-
-
PWY-8373
erythro-tetrahydrobiopterin biosynthesis I
-
-
PWY-5663
erythromycin D biosynthesis
-
-
PWY-7106
ethanol degradation I
-
-
ETOH-ACETYLCOA-ANA-PWY
ethanol degradation II
-
-
PWY66-21
ethanol degradation IV
-
-
PWY66-162
ethanolamine utilization
-
-
PWY0-1477
ethene biosynthesis III (microbes)
-
-
PWY-6854
ethene biosynthesis IV (engineered)
-
-
PWY-7126
ethene biosynthesis V (engineered)
-
-
PWY-7124
ethylmalonyl-CoA pathway
-
-
PWY-5741
farnesene biosynthesis
-
-
PWY-5725
fatty acid biosynthesis initiation (mitochondria)
-
-
PWY66-429
fatty acid biosynthesis initiation (plant mitochondria)
-
-
PWY-6799
fatty acid biosynthesis initiation (type I)
-
-
PWY-5966-1
fatty acid biosynthesis initiation (type II)
-
-
PWY-4381
fatty acid elongation -- saturated
-
-
FASYN-ELONG-PWY
fatty acid salvage
-
-
PWY-7094
Fe(II) oxidation
-
-
PWY-6692
firefly bioluminescence
-
-
PWY-7913
fluoroacetate and fluorothreonine biosynthesis
-
-
PWY-6644
folate transformations I
-
-
PWY-2201
folate transformations II (plants)
-
-
PWY-3841
folate transformations III (E. coli)
-
-
1CMET2-PWY
formaldehyde assimilation I (serine pathway)
-
-
PWY-1622
formaldehyde assimilation II (assimilatory RuMP Cycle)
-
-
PWY-1861
formaldehyde assimilation III (dihydroxyacetone cycle)
-
-
P185-PWY
formaldehyde oxidation I
-
-
RUMP-PWY
formaldehyde oxidation II (glutathione-dependent)
-
-
PWY-1801
formaldehyde oxidation VII (THF pathway)
-
-
PWY-7909
formate assimilation into 5,10-methylenetetrahydrofolate
-
-
PWY-1722
fructan degradation
-
-
PWY-862
GABA shunt I
-
-
GLUDEG-I-PWY
GABA shunt II
-
-
PWY-8346
gamma-glutamyl cycle
-
-
PWY-4041
GDP-alpha-D-glucose biosynthesis
-
-
PWY-5661
GDP-mannose biosynthesis
-
-
PWY-5659
gliotoxin biosynthesis
-
-
PWY-7533
gluconeogenesis I
-
-
GLUCONEO-PWY
gluconeogenesis II (Methanobacterium thermoautotrophicum)
-
-
PWY-6142
gluconeogenesis III
-
-
PWY66-399
glucose and glucose-1-phosphate degradation
-
-
GLUCOSE1PMETAB-PWY
glucose degradation (oxidative)
-
-
DHGLUCONATE-PYR-CAT-PWY
glutaryl-CoA degradation
-
-
PWY-5177
glutathione biosynthesis
-
-
GLUTATHIONESYN-PWY
glutathione-mediated detoxification I
-
-
PWY-4061
glutathione-mediated detoxification II
-
-
PWY-6842
glutathione-peroxide redox reactions
-
-
PWY-4081
glycerol degradation to butanol
-
-
PWY-7003
glycerol-3-phosphate to fumarate electron transfer
-
-
PWY0-1582
glycogen biosynthesis II (from UDP-D-Glucose)
-
-
PWY-5067
glycogen biosynthesis III (from alpha-maltose 1-phosphate)
-
-
PWY-7900
glycogen degradation I
-
-
GLYCOCAT-PWY
glycogen degradation II
-
-
PWY-5941
glycolysis I (from glucose 6-phosphate)
-
-
GLYCOLYSIS
glycolysis II (from fructose 6-phosphate)
-
-
PWY-5484
glycolysis III (from glucose)
-
-
ANAGLYCOLYSIS-PWY
glycolysis IV
-
-
PWY-1042
glycolysis V (Pyrococcus)
-
-
P341-PWY
glyoxylate assimilation
-
-
PWY-5744
glyoxylate cycle
-
-
GLYOXYLATE-BYPASS
glyphosate degradation III
-
-
PWY-7807
gondoate biosynthesis (anaerobic)
-
-
PWY-7663
gossypol biosynthesis
-
-
PWY-5773
guanine and guanosine salvage I
-
-
PWY-6620
guanine and guanosine salvage II
-
-
PWY-6599
guanosine deoxyribonucleotides de novo biosynthesis I
-
-
PWY-7226
guanosine deoxyribonucleotides de novo biosynthesis II
-
-
PWY-7222
guanosine nucleotides degradation I
-
-
PWY-6607
guanosine nucleotides degradation II
-
-
PWY-6606
guanosine nucleotides degradation III
-
-
PWY-6608
guanosine ribonucleotides de novo biosynthesis
-
-
PWY-7221
heme b biosynthesis I (aerobic)
-
-
HEME-BIOSYNTHESIS-II
heme b biosynthesis II (oxygen-independent)
-
-
HEMESYN2-PWY
heme b biosynthesis V (aerobic)
-
-
HEME-BIOSYNTHESIS-II-1
heme degradation I
-
-
PWY-5874
heparan sulfate biosynthesis
-
-
PWY-6558
heterolactic fermentation
-
-
P122-PWY
homoglutathione biosynthesis
-
-
PWY-6840
hydrogen to fumarate electron transfer
-
-
PWY0-1576
hydroxylated fatty acid biosynthesis (plants)
-
-
PWY-6433
hypoglycin biosynthesis
-
-
PWY-5826
icosapentaenoate biosynthesis I (lower eukaryotes)
-
-
PWY-6958
icosapentaenoate biosynthesis III (8-desaturase, mammals)
-
-
PWY-7724
icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)
-
-
PWY-7602
icosapentaenoate metabolites biosynthesis
-
-
PWY-8399
incomplete reductive TCA cycle
-
-
P42-PWY
indole glucosinolate activation (intact plant cell)
-
-
PWYQT-4477
indole-3-acetate biosynthesis II
-
-
PWY-581
indole-3-acetate biosynthesis III (bacteria)
-
-
PWY-3161
indole-3-acetate biosynthesis IV (bacteria)
-
-
PWY-5025
indole-3-acetate biosynthesis VI (bacteria)
-
-
TRPIAACAT-PWY
inosine 5'-phosphate degradation
-
-
PWY-5695
inositol diphosphates biosynthesis
-
-
PWY-6369
inulin degradation
-
-
PWY-8314
isoprene biosynthesis II (engineered)
-
-
PWY-7391
isopropanol biosynthesis (engineered)
-
-
PWY-6876
itaconate degradation
-
-
PWY-5749
jadomycin biosynthesis
-
-
PWY-6679
jasmonic acid biosynthesis
-
-
PWY-735
juniperonate biosynthesis
-
-
PWY-7619
justicidin B biosynthesis
-
-
PWY-6824
ketogenesis
-
-
PWY66-367
ketolysis
-
-
PWY66-368
L-alanine biosynthesis II
-
-
ALANINE-SYN2-PWY
L-alanine degradation II (to D-lactate)
-
-
ALACAT2-PWY
L-alanine degradation III
-
-
ALANINE-DEG3-PWY
L-alanine degradation V (oxidative Stickland reaction)
-
-
PWY-8189
L-alanine degradation VI (reductive Stickland reaction)
-
-
PWY-8188
L-arabinose degradation II
-
-
PWY-5515
L-arginine biosynthesis I (via L-ornithine)
-
-
ARGSYN-PWY
L-arginine biosynthesis II (acetyl cycle)
-
-
ARGSYNBSUB-PWY
L-arginine biosynthesis III (via N-acetyl-L-citrulline)
-
-
PWY-5154
L-arginine biosynthesis IV (archaea)
-
-
PWY-7400
L-arginine degradation X (arginine monooxygenase pathway)
-
-
ARGDEG-V-PWY
L-asparagine degradation III (mammalian)
-
-
ASPARAGINE-DEG1-PWY-1
L-aspartate biosynthesis
-
-
ASPARTATESYN-PWY
L-aspartate degradation I
-
-
ASPARTATE-DEG1-PWY
L-aspartate degradation II (aerobic)
-
-
PWY-8291
L-aspartate degradation III (anaerobic)
-
-
PWY-8294
L-carnitine degradation II
-
-
PWY-3641
L-glutamate biosynthesis II
-
-
GLUTAMATE-SYN2-PWY
L-glutamate biosynthesis III
-
-
GLUTSYNIII-PWY
L-glutamate degradation I
-
-
GLUTAMATE-DEG1-PWY
L-glutamate degradation II
-
-
GLUTDEG-PWY
L-glutamate degradation IX (via 4-aminobutanoate)
-
-
PWY0-1305
L-glutamate degradation V (via hydroxyglutarate)
-
-
P162-PWY
L-glutamate degradation X
-
-
PWY-5766
L-glutamate degradation XI (reductive Stickland reaction)
-
-
PWY-8190
L-glutamine biosynthesis I
-
-
GLNSYN-PWY
L-histidine degradation III
-
-
PWY-5030
L-histidine degradation V
-
-
PWY-5031
L-isoleucine degradation II
-
-
PWY-5078
L-leucine degradation I
-
-
LEU-DEG2-PWY
L-leucine degradation III
-
-
PWY-5076
L-lysine biosynthesis I
-
-
DAPLYSINESYN-PWY
L-lysine degradation II (L-pipecolate pathway)
-
-
PWY66-425
L-lysine degradation V
-
-
PWY-5283
L-lysine degradation XI
-
-
LYSINE-DEG1-PWY
L-lysine fermentation to acetate and butanoate
-
-
P163-PWY
L-malate degradation II
-
-
PWY-7686
L-methionine degradation I (to L-homocysteine)
-
-
METHIONINE-DEG1-PWY
L-methionine degradation III
-
-
PWY-5082
L-ornithine biosynthesis I
-
-
GLUTORN-PWY
L-ornithine biosynthesis II
-
-
ARGININE-SYN4-PWY
L-phenylalanine biosynthesis I
-
-
PHESYN
L-phenylalanine degradation I (aerobic)
-
-
PHENYLALANINE-DEG1-PWY
L-phenylalanine degradation II (anaerobic)
-
-
ANAPHENOXI-PWY
L-phenylalanine degradation III
-
-
PWY-5079
L-phenylalanine degradation IV (mammalian, via side chain)
-
-
PWY-6318
L-phenylalanine degradation V
-
-
PWY-7158
L-phenylalanine degradation VI (reductive Stickland reaction)
-
-
PWY-8014
L-selenocysteine biosynthesis I (bacteria)
-
-
PWY0-901
L-selenocysteine biosynthesis II (archaea and eukaryotes)
-
-
PWY-6281
L-serine biosynthesis I
-
-
SERSYN-PWY
L-threonine degradation V
-
-
PWY66-428
L-tryptophan degradation IV (via indole-3-lactate)
-
-
TRPKYNCAT-PWY
L-tryptophan degradation V (side chain pathway)
-
-
PWY-3162
L-tryptophan degradation VIII (to tryptophol)
-
-
PWY-5081
L-tryptophan degradation X (mammalian, via tryptamine)
-
-
PWY-6307
L-tryptophan degradation XIII (reductive Stickland reaction)
-
-
PWY-8017
L-tyrosine biosynthesis I
-
-
TYRSYN
L-tyrosine biosynthesis IV
-
-
PWY-6134
L-tyrosine degradation I
-
-
TYRFUMCAT-PWY
L-tyrosine degradation II
-
-
PWY-5151
L-tyrosine degradation III
-
-
PWY3O-4108
L-tyrosine degradation IV (to 4-methylphenol)
-
-
PWY-7514
L-tyrosine degradation V (reductive Stickland reaction)
-
-
PWY-8016
L-valine degradation II
-
-
PWY-5057
lacinilene C biosynthesis
-
-
PWY-5828
lactate fermentation to acetate, CO2 and hydrogen (Desulfovibrionales)
-
-
PWY-8377
lacto-series glycosphingolipids biosynthesis
-
-
PWY-7839
lanosterol biosynthesis
-
-
PWY-6132
leukotriene biosynthesis
-
-
PWY66-375
linamarin degradation
-
-
PWY-3121
linoleate metabolites biosynthesis
-
-
PWY-8395
linustatin bioactivation
-
-
PWY-7091
lipid A-core biosynthesis (E. coli K-12)
-
-
LIPA-CORESYN-PWY
lipid IVA biosynthesis (2,3-diamino-2,3-dideoxy-D-glucopyranose-containing)
-
-
PWY2B4Q-4
lipid IVA biosynthesis (E. coli)
-
-
NAGLIPASYN-PWY
lipid IVA biosynthesis (generic)
-
-
PWY-8283
lipid IVA biosynthesis (H. pylori)
-
-
PWYI-14
lipid IVA biosynthesis (P. gingivalis)
-
-
PWY-8245
lipid IVA biosynthesis (P. putida)
-
-
PWY-8073
lipid IVA biosynthesis (Vibrio cholerae serogroup O1 El Tor)
-
-
PWY2G6Z-2
lipoxin biosynthesis
-
-
PWY66-392
lotaustralin degradation
-
-
PWY-6002
luteolin triglucuronide degradation
-
-
PWY-7445
malate/L-aspartate shuttle pathway
-
-
MALATE-ASPARTATE-SHUTTLE-PWY
mangrove triterpenoid biosynthesis
-
-
PWY-6109
maresin biosynthesis
-
-
PWY-8356
matairesinol biosynthesis
-
-
PWY-5466
melatonin degradation I
-
-
PWY-6398
melibiose degradation
-
-
PWY0-1301
Methanobacterium thermoautotrophicum biosynthetic metabolism
-
-
PWY-6146
methanol oxidation to formaldehyde IV
-
-
PWY-5506
methiin metabolism
-
-
PWY-7614
methyl indole-3-acetate interconversion
-
-
PWY-6303
methyl phomopsenoate biosynthesis
-
-
PWY-7721
methyl tert-butyl ether degradation
-
-
PWY-7779
methylaspartate cycle
methylerythritol phosphate pathway I
-
-
NONMEVIPP-PWY
methylerythritol phosphate pathway II
-
-
PWY-7560
methylglyoxal degradation III
-
-
PWY-5453
methylglyoxal degradation IV
-
-
PWY-5459
methylglyoxal degradation V
-
-
PWY-5458
methylglyoxal degradation VI
-
-
MGLDLCTANA-PWY
methylsalicylate degradation
-
-
PWY18C3-24
methylwyosine biosynthesis
-
-
PWY-7285
mevalonate pathway I (eukaryotes and bacteria)
-
-
PWY-922
mevalonate pathway II (haloarchaea)
-
-
PWY-6174
mevalonate pathway III (Thermoplasma)
-
-
PWY-7524
mevalonate pathway IV (archaea)
-
-
PWY-8125
mitochondrial NADPH production (yeast)
-
-
PWY-7269
mixed acid fermentation
-
-
FERMENTATION-PWY
molybdenum cofactor biosynthesis
-
-
PWY-8171
mono-trans, poly-cis decaprenyl phosphate biosynthesis
-
-
PWY-6383
mRNA capping I
-
-
PWY-7375
mucin core 3 and core 4 O-glycosylation
-
-
PWY-7435
mupirocin biosynthesis
-
-
PWY-8012
mycobactin biosynthesis
-
-
PWY185E-1
mycolate biosynthesis
-
-
PWYG-321
mycolyl-arabinogalactan-peptidoglycan complex biosynthesis
-
-
PWY-6397
mycothiol biosynthesis
-
-
PWY1G-0
myo-inositol biosynthesis
N-acetylglucosamine degradation I
-
-
GLUAMCAT-PWY
NAD phosphorylation and dephosphorylation
-
-
NADPHOS-DEPHOS-PWY
NAD phosphorylation and transhydrogenation
-
-
NADPHOS-DEPHOS-PWY-1
NAD salvage (plants)
-
-
PWY-5381
NAD salvage pathway III (to nicotinamide riboside)
-
-
NAD-BIOSYNTHESIS-II
NAD salvage pathway V (PNC V cycle)
-
-
PWY3O-4107
NAD(P)/NADPH interconversion
-
-
PWY-5083
NADH to cytochrome bd oxidase electron transfer I
-
-
PWY0-1334
NADH to cytochrome bo oxidase electron transfer I
-
-
PWY0-1335
NADH to fumarate electron transfer
-
-
PWY0-1336
NADP biosynthesis
-
-
PWY-8148
NADPH to cytochrome c oxidase via plastocyanin
-
-
PWY-8271
neolacto-series glycosphingolipids biosynthesis
-
-
PWY-7841
neolinustatin bioactivation
-
-
PWY-7092
nicotine degradation I (pyridine pathway)
-
-
P181-PWY
nicotine degradation IV
-
-
PWY66-201
nicotine degradation V
-
-
PWY66-221
nitrate reduction I (denitrification)
-
-
DENITRIFICATION-PWY
nitrate reduction VII (denitrification)
-
-
PWY-6748
nitric oxide biosynthesis II (mammals)
-
-
PWY-4983
nitrifier denitrification
-
-
PWY-7084
nitrite-dependent anaerobic methane oxidation
-
-
PWY-6523
nitrogen remobilization from senescing leaves
-
-
PWY-6549
nocardicin A biosynthesis
-
-
PWY-7797
noradrenaline and adrenaline degradation
-
-
PWY-6342
nucleoside and nucleotide degradation (archaea)
-
-
PWY-5532
o-diquinones biosynthesis
-
-
PWY-6752
octane oxidation
-
-
P221-PWY
octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)
-
-
PWY-7388
oleandomycin activation/inactivation
-
-
PWY-6972
oleate beta-oxidation
-
-
PWY0-1337
oleate biosynthesis II (animals and fungi)
-
-
PWY-5996
oleate biosynthesis IV (anaerobic)
-
-
PWY-7664
ophthalmate biosynthesis
-
-
PWY-8043
palmitate biosynthesis II (type II fatty acid synthase)
-
-
PWY-5971
palmitate biosynthesis III
-
-
PWY-8279
palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)
-
-
PWY-6282
palmitoleate biosynthesis IV (fungi and animals)
-
-
PWY3O-1801
partial TCA cycle (obligate autotrophs)
-
-
PWY-5913
pederin biosynthesis
-
-
PWY-8049
pentachlorophenol degradation
-
-
PCPDEG-PWY
pentose phosphate pathway (non-oxidative branch) I
-
-
NONOXIPENT-PWY
pentose phosphate pathway (non-oxidative branch) II
-
-
PWY-8178
pentose phosphate pathway (oxidative branch) I
-
-
OXIDATIVEPENT-PWY
pentose phosphate pathway (partial)
-
-
P21-PWY
peptido-conjugates in tissue regeneration biosynthesis
-
-
PWY-8355
peptidoglycan biosynthesis II (staphylococci)
-
-
PWY-5265
peptidoglycan biosynthesis IV (Enterococcus faecium)
-
-
PWY-6471
peptidoglycan maturation (meso-diaminopimelate containing)
-
-
PWY0-1586
peptidoglycan recycling I
-
-
PWY0-1261
peptidoglycan recycling II
-
-
PWY-7883
periplasmic disulfide bond formation
-
-
PWY0-1599
petrobactin biosynthesis
-
-
PWY-6289
phenylethanol biosynthesis
-
-
PWY-5751
phenylpropanoid biosynthesis
-
-
PWY-361
phenylpropanoid biosynthesis, initial reactions
-
-
PWY1F-467
phenylpropanoids methylation (ice plant)
-
-
PWY-7498
phosphate acquisition
-
-
PWY-6348
phosphatidate metabolism, as a signaling molecule
-
-
PWY-7039
phosphatidylcholine acyl editing
-
-
PWY-6803
phosphatidylinositol biosynthesis I (bacteria)
-
-
PWY-6580
phospholipases
-
-
LIPASYN-PWY
phospholipid remodeling (phosphatidate, yeast)
-
-
PWY-7417
phospholipid remodeling (phosphatidylcholine, yeast)
-
-
PWY-7416
phospholipid remodeling (phosphatidylethanolamine, yeast)
-
-
PWY-7409
phosphopantothenate biosynthesis I
-
-
PANTO-PWY
photosynthetic 3-hydroxybutanoate biosynthesis (engineered)
-
-
PWY-7218
phytate degradation I
-
-
PWY-4702
phytate degradation II
-
-
PWY-4781
phytol degradation
-
-
PWY66-389
phytosterol biosynthesis (plants)
-
-
PWY-2541
plasmalogen biosynthesis I (aerobic)
-
-
PWY-7782
plasmalogen degradation
-
-
PWY-7783
poly-hydroxy fatty acids biosynthesis
-
-
PWY-6710
polyhydroxybutanoate biosynthesis
-
-
PWY1-3
polyphosphate metabolism
-
-
PWY-8138
ppGpp metabolism
-
-
PPGPPMET-PWY
preQ0 biosynthesis
-
-
PWY-6703
procollagen hydroxylation and glycosylation
-
-
PWY-7894
propanethial S-oxide biosynthesis
-
-
PWY-5707
protectin biosynthesis
-
-
PWY-8357
protein N-glycosylation initial phase (eukaryotic)
-
-
MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
protein N-glycosylation processing phase (endoplasmic reticulum, yeast)
-
-
PWY-7918
protein N-glycosylation processing phase (plants and animals)
-
-
PWY-7919
protein NEDDylation
-
-
PWY-7899
protein ubiquitination
-
-
PWY-7511
pseudouridine degradation
-
-
PWY-6019
purine deoxyribonucleosides degradation I
-
-
PWY-7179
purine deoxyribonucleosides degradation II
-
-
PWY-7179-1
purine deoxyribonucleosides salvage
-
-
PWY-7224
purine nucleobases degradation I (anaerobic)
-
-
P164-PWY
purine nucleobases degradation II (anaerobic)
-
-
PWY-5497
purine ribonucleosides degradation
-
-
PWY0-1296
putrescine biosynthesis III
-
-
PWY-46
pyridoxal 5'-phosphate salvage I
-
-
PLPSAL-PWY
pyridoxal 5'-phosphate salvage II (plants)
-
-
PWY-7204
pyrimidine deoxyribonucleosides degradation
-
-
PWY-7181
pyrimidine deoxyribonucleosides salvage
-
-
PWY-7199
pyrimidine deoxyribonucleotide phosphorylation
-
-
PWY-7197
pyrimidine deoxyribonucleotides biosynthesis from CTP
-
-
PWY-7210
pyrimidine deoxyribonucleotides de novo biosynthesis I
-
-
PWY-7184
pyrimidine deoxyribonucleotides de novo biosynthesis II
-
-
PWY-7187
pyrimidine deoxyribonucleotides de novo biosynthesis III
-
-
PWY-6545
pyrimidine deoxyribonucleotides de novo biosynthesis IV
-
-
PWY-7198
pyrimidine deoxyribonucleotides dephosphorylation
-
-
PWY-7206
pyrimidine ribonucleosides degradation
-
-
PWY0-1295
pyrrolnitrin biosynthesis
-
-
PWY-6831
pyruvate fermentation to (R)-lactate
-
-
PWY-8274
pyruvate fermentation to (S)-lactate
-
-
PWY-5481
pyruvate fermentation to acetate II
-
-
PWY-5482
pyruvate fermentation to acetate V
-
-
PWY-5537
pyruvate fermentation to acetone
-
-
PWY-6588
pyruvate fermentation to butanoate
-
-
CENTFERM-PWY
pyruvate fermentation to butanol I
-
-
PWY-6583
pyruvate fermentation to butanol II (engineered)
-
-
PWY-6883
pyruvate fermentation to ethanol I
-
-
PWY-5480
pyruvate fermentation to ethanol II
-
-
PWY-5486
pyruvate fermentation to ethanol III
-
-
PWY-6587
pyruvate fermentation to hexanol (engineered)
-
-
PWY-6863
pyruvate fermentation to isobutanol (engineered)
-
-
PWY-7111
pyruvate fermentation to propanoate I
-
-
P108-PWY
queuosine biosynthesis I (de novo)
-
-
PWY-6700
queuosine biosynthesis III (queuosine salvage)
-
-
PWY-8106
Rapoport-Luebering glycolytic shunt
-
-
PWY-6405
reactive oxygen species degradation
-
-
DETOX1-PWY-1
rebeccamycin biosynthesis
-
-
PWY-6324
reductive acetyl coenzyme A pathway I (homoacetogenic bacteria)
-
-
CODH-PWY
reductive glycine pathway of autotrophic CO2 fixation
-
-
PWY-8303
reductive TCA cycle I
-
-
P23-PWY
reductive TCA cycle II
-
-
PWY-5392
resolvin D biosynthesis
-
-
PWY66-397
retinol biosynthesis
-
-
PWY-6857
rosmarinic acid biosynthesis I
-
-
PWY-5048
Rubisco shunt
-
-
PWY-5723
S-adenosyl-L-methionine salvage II
-
-
PWY-5041
salidroside biosynthesis
-
-
PWY-6802
salinosporamide A biosynthesis
-
-
PWY-6627
sciadonate biosynthesis
-
-
PWY-6598
scopoletin biosynthesis
-
-
PWY-6792
sedoheptulose bisphosphate bypass
-
-
PWY0-1517
serine racemization
-
-
PWY-8140
serotonin degradation
-
-
PWY-6313
sesamin biosynthesis
-
-
PWY-5469
solasodine glycosylation
-
-
PWY18C3-4
sorgoleone biosynthesis
-
-
PWY-5987
spermidine biosynthesis I
-
-
BSUBPOLYAMSYN-PWY
spermidine biosynthesis III
-
-
PWY-6834
spermine biosynthesis
-
-
ARGSPECAT-PWY
sphingolipid biosynthesis (mammals)
-
-
PWY-7277
sphingolipid biosynthesis (plants)
-
-
PWY-5129
sphingomyelin metabolism
-
-
PWY3DJ-11281
sphingosine and sphingosine-1-phosphate metabolism
-
-
PWY3DJ-11470
sporopollenin precursors biosynthesis
-
-
PWY-6733
stachyose degradation
-
-
PWY-6527
starch biosynthesis
-
-
PWY-622
starch degradation I
-
-
PWY-842
starch degradation III
-
-
PWY-6731
starch degradation IV
-
-
PWY-6735
starch degradation V
-
-
PWY-6737
stearate biosynthesis I (animals)
-
-
PWY-5972
stearate biosynthesis II (bacteria and plants)
-
-
PWY-5989
stearate biosynthesis III (fungi)
-
-
PWY3O-355
stearate biosynthesis IV
-
-
PWY-8280
stellatic acid biosynthesis
-
-
PWY-7736
sterol:steryl ester interconversion (yeast)
-
-
PWY-7424
streptorubin B biosynthesis
-
-
PWY1A0-6120
suberin monomers biosynthesis
succinate to chytochrome c oxidase via cytochrome c6
-
-
PWY1YI0-2
succinate to cytochrome bd oxidase electron transfer
-
-
PWY0-1353
succinate to cytochrome bo oxidase electron transfer
-
-
PWY0-1329
succinate to cytochrome c oxidase via plastocyanin
-
-
PWY1YI0-3
succinate to plastoquinol oxidase
-
-
PWY1YI0-8
sucrose biosynthesis I (from photosynthesis)
-
-
SUCSYN-PWY
sucrose biosynthesis II
-
-
PWY-7238
sucrose biosynthesis III
-
-
PWY-7347
sucrose degradation II (sucrose synthase)
-
-
PWY-3801
sucrose degradation III (sucrose invertase)
-
-
PWY-621
sucrose degradation IV (sucrose phosphorylase)
-
-
PWY-5384
sucrose degradation V (sucrose alpha-glucosidase)
-
-
PWY66-373
sulfide oxidation IV (mitochondria)
-
-
PWY-7927
sulfolactate degradation III
-
-
PWY-6638
superoxide radicals degradation
-
-
DETOX1-PWY
superpathway of fatty acid biosynthesis initiation
-
-
FASYN-INITIAL-PWY
superpathway of fermentation (Chlamydomonas reinhardtii)
-
-
PWY4LZ-257
superpathway of glucose and xylose degradation
-
-
PWY-6901
superpathway of glycolysis and the Entner-Doudoroff pathway
-
-
GLYCOLYSIS-E-D
superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass
-
-
GLYCOLYSIS-TCA-GLYOX-BYPASS
superpathway of glyoxylate cycle and fatty acid degradation
-
-
PWY-561
superpathway of methylsalicylate metabolism
-
-
PWY18C3-25
superpathway of ornithine degradation
-
-
ORNDEG-PWY
superpathway of photosynthetic hydrogen production
-
-
PWY-7731
superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli)
-
-
PWY0-166
superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis
-
-
PWY-7328
TCA cycle I (prokaryotic)
-
-
TCA
TCA cycle II (plants and fungi)
-
-
PWY-5690
TCA cycle III (animals)
-
-
PWY66-398
TCA cycle IV (2-oxoglutarate decarboxylase)
-
-
P105-PWY
TCA cycle V (2-oxoglutarate synthase)
-
-
PWY-6969
TCA cycle VI (Helicobacter)
-
-
REDCITCYC
TCA cycle VII (acetate-producers)
-
-
PWY-7254
TCA cycle VIII (Chlamydia)
-
-
TCA-1
tea aroma glycosidic precursor bioactivation
-
-
PWY-7114
terminal O-glycans residues modification (via type 2 precursor disaccharide)
-
-
PWY-7434
tetradecanoate biosynthesis (mitochondria)
-
-
PWY66-430
tetrahydrofolate biosynthesis I
-
-
PWY-6614
tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate
-
-
PWY-6613
tetrahydromonapterin biosynthesis
-
-
PWY0-1433
tetrahydropteridine recycling
-
-
PWY-8099
thioredoxin pathway
-
-
THIOREDOX-PWY
thiosulfate disproportionation IV (rhodanese)
-
-
PWY-5350
threo-tetrahydrobiopterin biosynthesis
-
-
PWY-6983
thymine degradation
-
-
PWY-6430
thyroid hormone metabolism I (via deiodination)
-
-
PWY-6260
thyroid hormone metabolism II (via conjugation and/or degradation)
-
-
PWY-6261
trans, trans-farnesyl diphosphate biosynthesis
-
-
PWY-5123
trans-zeatin biosynthesis
-
-
PWY-2681
traumatin and (Z)-3-hexen-1-yl acetate biosynthesis
-
-
PWY-5410
trehalose biosynthesis I
-
-
TRESYN-PWY
trehalose biosynthesis IV
-
-
PWY-2622
trehalose degradation I (low osmolarity)
-
-
TREDEGLOW-PWY
trehalose degradation II (cytosolic)
-
-
PWY0-1182
trehalose degradation IV
-
-
PWY-2722
trehalose degradation V
-
-
PWY-2723
trehalose degradation VI (periplasmic)
-
-
PWY0-1466
triacylglycerol degradation
-
-
LIPAS-PWY
tRNA charging
-
-
TRNA-CHARGING-PWY
tRNA methylation (yeast)
-
-
PWY-6829
tRNA processing
-
-
PWY0-1479
tunicamycin biosynthesis
-
-
PWY-7821
type I lipoteichoic acid biosynthesis (S. aureus)
-
-
PWY-7817
UDP-alpha-D-galactose biosynthesis
-
-
PWY-7344
UDP-alpha-D-glucose biosynthesis
-
-
PWY-7343
UDP-N-acetyl-D-galactosamine biosynthesis II
-
-
PWY-5514
UDP-N-acetyl-D-galactosamine biosynthesis III
-
-
PWY-8013
UDP-N-acetyl-D-glucosamine biosynthesis I
-
-
UDPNAGSYN-PWY
UDP-N-acetyl-D-glucosamine biosynthesis II
-
-
UDPNACETYLGALSYN-PWY
ultra-long-chain fatty acid biosynthesis
-
-
PWY-8041
UMP biosynthesis I
-
-
PWY-5686
UMP biosynthesis II
-
-
PWY-7790
UMP biosynthesis III
-
-
PWY-7791
uracil degradation I (reductive)
-
-
PWY-3982
urate conversion to allantoin I
-
-
PWY-5691
urea cycle
UTP and CTP de novo biosynthesis
-
-
PWY-7176
UTP and CTP dephosphorylation I
-
-
PWY-7185
UTP and CTP dephosphorylation II
-
-
PWY-7177
valproate beta-oxidation
-
-
PWY-8182
vancomycin resistance I
-
-
PWY-6454
vancomycin resistance II
-
-
PWY-6455
vanillin biosynthesis I
-
-
PWY-5665
very long chain fatty acid biosynthesis I
-
-
PWY-5080
very long chain fatty acid biosynthesis II
-
-
PWY-7036
vitamin K-epoxide cycle
xanthine and xanthosine salvage
-
-
SALVPURINE2-PWY
xanthommatin biosynthesis
-
-
PWY-8249
xyloglucan degradation II (exoglucanase)
-
-
PWY-6807
zymosterol biosynthesis
-
-
PWY-6074
cyanate degradation
-
-
CYANCAT-PWY
methylaspartate cycle
-
-
PWY-6728
myo-inositol biosynthesis
-
-
PWY-2301
suberin monomers biosynthesis
-
-
PWY-1121
urea cycle
-
-
PWY-4984
vitamin K-epoxide cycle
-
-
PWY-7999
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
790, 791, 792, 795, 1386, 1536, 1552, 2843, 34826, 35977, 36180, 36189, 36956, 134458, 134674, 134923, 135122, 136151, 136166, 137126, 171237, 171693, 208704, 209110, 209837, 210553, 246818, 286030, 286646, 287013, 326291, 348931, 349002, 391549, 391585, 391605, 391663, 393230, 393719, 394175, 395992, 396070, 486030, 488034, 488425, 488451, 488597, 488873, 488874, 489364, 489376, 637232, 637234, 637235, 637993, 638424, 638425, 638426, 638515, 640421, 640776, 640780, 640793, 641053, 641522, 642662, 642682, 643496, 643497, 643650, 643747, 643748, 644114, 645152, 646409, 647182, 649082, 649264, 649701, 650289, 653100, 656005, 656629, 656707, 659073, 659797, 661157, 663962, 664803, 666498, 667080, 667828, 668611, 669475, 675444, 678049, 679129, 680655, 682285, 682527, 682938, 682957, 683344, 683389, 683926, 685354, 685395, 685819, 685820, 686296, 687577, 688691, 689741, 689758, 691390, 691699, 692177, 692365, 694894, 695339, 696812, 700379, 701716, 704551, 706869, 707630, 708284, 708577, 709568, 710756, 711714, 712426, 714181, 721541, 721632, 723543, 724169, 726663, 726665, 727519, 731338, 731572, 733408, 733767, 734639, 735286, 736771, 736905, 737654, 741263, 750325, 751181, 755866, 759008, 759073
-
-
-
490278, 490279, 490999, 491000, 491001, 491131, 491265, 491266, 491527, 491528, 491564, 491703, 491759, 640789, 640791, 640963, 650944, 658198, 660905, 662275, 668743, 669447, 669475, 681829, 693303, 696304, 703518, 721946, 722248, 722716, 723767, 738660, 739690, 747858, 749332, 758882
O96759, P10901, P18160, P25323, P28178, P34099, P34112, P34117, P34125, P42525, P42527, P51136, P54673, P54674, P54675, P54676, P54685, P90648, Q27564, Q54HH2, Q54JI7, Q54RV9, Q55DL0, Q86H13, Q8MY12, Q8MZN0, Q963L5
SwissProt
-
134684, 642668, 642673, 642679, 654524, 674423, 675444, 689078, 690742, 693656, 700951, 706871, 719606, 725004, 729559, 733689, 733943, 735513, 739856, 741341, 744104, 744151, 746983, 747967, 748651, 753394, 754027, 756304, 756637, 757288, 759753, 761088, 761202, 761257, 764924, 765047
O15757, P08799, P20425, P22887, Q23917, Q54BM7, Q54CJ4, Q54E29, Q54HW0, Q54J94, Q54L33, Q54MH8, Q54N49, Q54P86, Q54TD0, Q54UF3, Q54UT2, Q54VL5, Q54WD4, Q54X84, Q556V8, Q55AX0, Q55EI0, Q55EZ0, Q55F94, Q55FC8, Q55FE6, Q6IMN8, Q6TMK4, Q75JI3, Q7KWU0, Q86A17, Q86AD9, Q86IE7, Q86KR9, Q94502, Q9XZE5
UniProt
GCA, another guanylyl cylase, i.e. soluble guanylyl cyclase (sGC), is present in Dictyostelium
-
-
genes CCT1-8 encoding subunits CCT-alpha, CCT-beta, CCT-gamma, CCT-delta, CCT-epsilon or CCT5 isoform A, CCT-zeta, CCT-eta, and CCT-theta
Q55BM4, Q54ES9, Q54TH8, Q54CL2, Q54TD3, Q76NU3, Q54ER7, Q552J0
UniProt
His-tagged motor domain construct comprising amino acids 1-761
UniProt
isoform PDE4, enzyme is expressed during single cell stages and expression increases after 9 h of starvation
SwissProt
isozyme PLDA; three isozymes PLDA, PLDB, and PDLC, encoded by genes plda, pldb, and pldc
UniProt
isozyme PLDB; three isozymes PLDA, PLDB, and PDLC, encoded by genes plda, pldb, and pldc
UniProt
isozyme PLDC; three isozymes PLDA, PLDB, and PDLC, encoded by genes plda, pldb, and pldc
UniProt
NC-4, haploid wild-type and its mutant Fr-17, slime mould, not mutants Fr-2 and AGG-204
-
-
P4H1 is the Dictyostelium ortholog of human PHD2 except that it modifies Skp1 rather than HIF1alpha
-
-
PFK mRNA, PFK protein levels and PFK activity slowly decrease during development
SwissProt
precursor; comparative and phylogenetic analysis of alpha-L-fucosidase genes
SwissProt
soluble guanylyl cyclase (sGC), another guanylyl cylase, i.e. GCA, is present in Dictyostelium
-
-
two heavy chain kinases: one in growth-phase cells and one in starved, developing cells
-
-
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
-
specifically localized in. Activity sharply changes in response to differentiation and dedifferentiation
-
upon development, mRNA expression of guanylyl cyclase GCA decreases about 5fold during aggregation and subsequently rises, reaching a maximum during the slug stage
additional information
-
soluble guanylyl cyclase sGC is mainly expressed during aggregation phase
-
upon development, mRNA expression of guanylyl cyclase GCA decreases about 5fold during aggregation and subsequently rises, reaching a maximum during the slug stage
-
the starting cells, which are harvested just after plating on the developmental plate exhibit high PTPS mRNA. After 4 h, the transcripts decrease dramatically and then remain at the levels thereafter, although increases slightly at the terminal stage (after 12 h)
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overexpresssing cells show slower growth and increased cell size
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activity appears shortly before actual synthesis of galactose-containing mucopolysaccharides, it reaches a peak of activity shortly before the end of fruiting body construction and then disappears
sGC protein enriched at the leading edge of the cell during chemotaxis
additional information
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Ax4 cell, HDB7YA cell (smlA- cell), HDB2B/4 cell (cells with low counting factor)
additional information
both ODC transcript and protein are expressed at all stages of development and show high expression in prestalk/stalk cells
additional information
Dictyostelium discoideum harbors at least six genes encoding TPP1, tpp1A to tpp1F. The tpp1F gene is transcribed throughout development and translated into a polypeptide. TPPIF transcript is very abundant throughout development and is particularly high at the vegetative stage, but the amounts of the protein are lower during growth (t0) than during development
additional information
enzyme expression only during development
additional information
enzyme is expressed during growth, but decreases in amount after starvation
additional information
expression analysis of the alpha-subunit of MPP during development, highest levels in vegetatively growing cells and during early development, marked downregulation after 10 h, alpha-MPPL and MPP activities completely disappear around the slug stage, overview
additional information
expression levels and patterns of Ddpngase are developmentally regulated. Higher level of enzyme expression during the aggregate stage. The expression gets restricted to the prestalk region during later developmental stages
additional information
expression of DdPoxA is upregulated at late developmental stages, starting approximately from 12 h after initiation of starvation
additional information
-
in all cells, expression of an O2-dependent prolyl-4-hydroxylase P4H1
additional information
methylglyoxal (MG) level significantly increases and ROS level is maintained at high levels after mound stage
additional information
-
most abundant in tissues which display active polysaccharide synthesis
additional information
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SR gene expression and activity in different developmental stages
additional information
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tenfold increase in 2-oxoglutarate dehydrogenase complex activity between the amoeba stage and the aggregation stage, 2fold increase between the aggregation stage and the sorocarp stage
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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
-
integral membrane protein, at least the catalytic center is on the luminal site of the vesicles
-
beta and alpha subunit of MPP, Western blot of the mitochondrial subfractions
-
beta subunit of MPP, not alpha subunit of MPP, Western blot of the mitochondrial subfractions
additional information
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210553, 286646, 488248, 658198, 659358, 686499, 687577, 688691, 689741, 735286, 751171, 754027, 756637
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diffuse in nonmotile amoebae. Concentration with F-actin in pseudopods at the front of motile, chemotaxing cells, but not present in filopodia or at the very leading edge
MHCK A associates with the cytoskeleton and localizes to the cell cortex
P42527, Q27564, Q54UF3, Q55BM4 AND Q54ES9 AND Q54TH8 AND Q54CL2 AND Q54TD3 AND Q76NU3 AND Q54ER7 AND Q552J0, Q55EI0, Q6IMN8, Q86KR9, Q8T1C6, Q9XZE5
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1552, 134684, 137126, 489364, 639555, 639557, 640421, 640776, 640777, 640801, 646409, 660905, 661614, 667002, 674423, 723543, 736771, 747967, 749858, 759753, 761257
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activity of glucose-6-phosphatase in crude cytosol is positively correlated with the amount of secreted multipolypeptide complex called counting factor
the recombinant fluorescent-tagged enzyme is also present to a lower extent in the cytosol
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isoform ZntB is the main Zn2+ transporter of the endosome
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increasing activity up to aggregation stage, not detectable in the growth phase
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-
isoform ZntB is the main Zn2+ transporter of the lysosome
association of the enzyme to membranes enhances the activity
DdPDE4 is a unique membrane-bound phosphodiesterase with an extracellular catalytic domain regulating intercellular cAMP during multicellular development
membrane-bound enzyme with an extracellular domain
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activity of glucose-6-phosphatase in crude microsome is negatively correlated with the amount of secreted multipolypeptide complex called counting factor
-
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both isoforms Cca1 and CCa2 are not specifically enriched in mitochondria
Twinkle homologue (Twm1) in Dictyostelium discoideum is encoded by the nuclear twm1 gene and targeted to mitochondria
the recombinant fluorescent-tagged enzyme colocalizes in the nucleus along with DAPI blue stained DNA
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Dd5P4 accumulates on Legionella-containing vacuoles in wild-type Legionella pneumophilia infected Dictyostelium discoideum
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isoform ZntA is the main Zn2+ transporter of the contractile vacuole
additional information
DdAte1-GFP localization in the cytosol and nucleus is more persistent than in transient pseudopodial protruxadsions. DdAte1-GFP expressing cells are measured in nuclei, cytosol, and lamellipodia. DdAte1-GFP is slightly more prominent in cortical protrusions than in the nucleus. Localization analysis of GFP-tagged Ate1, overview
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additional information
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enzyme is specifically localized in the smaller vesicles with lighter density than the prespore-specific vacuoles identifiable electron microscopically
-
additional information
enzyme possesses no nuclear or transmembrane sequences
-
additional information
isoform DlpA localization is detected at the cleavage furrow in cells during telophase and at sites where cells has divided
-
additional information
localized in close proximity to the proteasomal machinery
-
additional information
MHCK A is localized to actin-rich regions in mitotic cells
-
additional information
-
the 3 isozymes MHCK A, MHCK B, and MHCK C show differential localization patterns in living cells, overview
-
additional information
-
the enzyme colocalises with actin and calmodulin, but not with macropinosomes
-
additional information
the enzyme is predominantly perinuclear but also cytosolic, subcellular localization analysis
-
additional information
the enzyme's coiled-coil structure mediates its oligomerization, cellular localization, and actin-binding activity of the MHCK A
-
additional information
TPP1F contains an N-terminal hydrophobic sequence, which is predicted as a signal sequence. The N-terminal signal sequence is essential for transport of the protein across the endoplasmic reticulum membrane and is presumably cleaved off
-
additional information
translocation of the enzyme within the cell responding to outer signals
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LINKS TO OTHER DATABASES (specific for Dictyostelium discoideum)
SILVA: 16S/18S rRNA, 23S/28S rRNA
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Release 2023.1 (January 2023)
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