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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
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1.3.1.B13
a dolichol + NADP+
reduction of the alpha-isoprene subunit of polyprenol
Homo sapiens
a polyprenol + NADPH + H+
-
?
1.3.1.B13
a polyprenol + NADPH + H+
-
Homo sapiens
a dolichol + NADP+
-
?
1.3.1.B13
a polyprenol + NADPH + H+
-
Arabidopsis thaliana
a dolichol + NADP+
-
?
1.3.1.B13
a polyprenol + NADPH + H+
the enzyme (SRD5A3) is necessary for the reduction of the alpha-isoprene unit of polyprenols to form alpha-reduced dolichols, required for synthesis of dolichol-linked monosaccharides, and the oligosaccharide precursor used for N-glycosylation. The presence of residual dolichol in cells depleted for this enzyme suggests the existence of an unexpected alternative pathway for dolichol de novo biosynthesis
Homo sapiens
a dolichol + NADP+
-
?
1.3.1.B13
a polyprenol + NADPH + H+
-
Arabidopsis thaliana Col-0
a dolichol + NADP+
-
?
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