EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
    1.5.1.27 | 1,2-dehydroreticulinium + NADPH + H+ |
no activity in the back reaction |
Papaver somniferum |
(R)-reticuline + NADP+ |
- |
ir |
| 1.5.1.27 | 1,2-dehydroreticulinium + NADPH + H+ |
under conditions favoring oxidation, PrDRR converts (R)-reticuline, but not (S)-reticuline, to 1,2-dehydroreticuline |
Papaver rhoeas |
(R)-reticuline + NADP+ |
- |
r |
| 1.5.1.27 | 1,2-dehydroreticulinium + NADPH + H+ |
under conditions favoring oxidation, PsDRR1 converts (R)-reticuline, but not (S)-reticuline, to 1,2-dehydroreticuline |
Papaver somniferum |
(R)-reticuline + NADP+ |
- |
r |
| 1.5.1.27 | 1,2-dehydroreticulinium + NADPH + H+ |
the enzyme catalyzes a stereospecific reduction of the C=N double bond in 1,2-dehydroreticuline to (R)-reticuline |
Papaver somniferum |
(R)-reticuline + NADP+ |
- |
? |
| 1.5.1.27 | more |
the bifunctional CYP82Y2 fusion enzyme termed reticuline epimerase (PsREPI) is a fusion between a cytochrome P450 (CYP) and an aldo-keto reductase (AKR) catalyzes the S-to-R epimerization of reticuline via 1,2-dehydroreticuline |
Papaver somniferum |
? |
- |
? |
| 1.5.1.27 | more |
enzyme PsREPI also catalyzes the stereochemical inversion of (S)-N-methylcoclaurine |
Papaver somniferum |
? |
- |
? |
