1.5.1.27	1,2-dehydro-N-methylcoclaurine + NADPH + H+	PrDRR reduces 1,2-dehydro-N-methylcoclaurine to N-methylcoclaurine, although the low product yield precludes determination of the enantiomer	Papaver rhoeas	N-methylcoclaurine + NADP+	-	?	440474	
1.5.1.27	1,2-dehydro-N-methylcoclaurine + NADPH + H+	PsDRR1 reduces 1,2-dehydro-N-methylcoclaurine to N-methylcoclaurine, although the low product yield precludes determination of the enantiomer	Papaver somniferum	N-methylcoclaurine + NADP+	-	?	440474	
1.5.1.27	1,2-Dehydroreticuline + NADPH	formation of the precursor of morphinan alkaloids	Papaver somniferum	?	-	?	369502	
1.5.1.27	1,2-Dehydroreticuline + NADPH	the enzyme catalyzes the provision of (R)-reticuline for the formation of morphinian alkaloids that possess also (R)-configuration at the chiral centre	Papaver somniferum	?	-	?	369502	
1.5.1.27	1,2-dehydroreticuline + NADPH + H+	-	Papaver somniferum	(R)-reticuline + NADP+	-	?	6445	
1.5.1.27	1,2-dehydroreticuline + NADPH + H+	-	Papaver bracteatum	(R)-reticuline + NADP+	-	?	6445	
1.5.1.27	1,2-dehydroreticulinium + NADPH + H+	-	Papaver somniferum	(R)-reticuline + NADP+	-	r	440053	
1.5.1.27	1,2-dehydroreticulinium + NADPH + H+	-	Papaver rhoeas	(R)-reticuline + NADP+	-	r	440053	
1.5.1.27	1,2-dehydroreticulinium + NADPH + H+	-	Papaver somniferum	(R)-reticuline + NADP+	-	?	440053	
1.5.1.27	1,2-dehydroreticulinium + NADPH + H+	-	Papaver somniferum	(R)-reticuline + NADP+	-	ir	440053	
1.5.1.27	1,2-dehydroreticulinium + NADPH + H+	no activity in the back reaction	Papaver somniferum	(R)-reticuline + NADP+	-	ir	440053	
1.5.1.27	1,2-dehydroreticulinium + NADPH + H+	under conditions favoring oxidation, PrDRR converts (R)-reticuline, but not (S)-reticuline, to 1,2-dehydroreticuline	Papaver rhoeas	(R)-reticuline + NADP+	-	r	440053	
1.5.1.27	1,2-dehydroreticulinium + NADPH + H+	under conditions favoring oxidation, PsDRR1 converts (R)-reticuline, but not (S)-reticuline, to 1,2-dehydroreticuline	Papaver somniferum	(R)-reticuline + NADP+	-	r	440053	
1.5.1.27	1,2-dehydroreticulinium + NADPH + H+	the enzyme catalyzes a stereospecific reduction of the C=N double bond in 1,2-dehydroreticuline to (R)-reticuline	Papaver somniferum	(R)-reticuline + NADP+	-	?	440053	
1.5.1.27	additional information	the bifunctional CYP82Y2 fusion enzyme termed reticuline epimerase (PsREPI) is a fusion between a cytochrome P450 (CYP) and an aldo-keto reductase (AKR) catalyzes the S-to-R epimerization of reticuline via 1,2-dehydroreticuline	Papaver somniferum	?	-	?	89	
1.5.1.27	additional information	enzyme PsREPI also catalyzes the stereochemical inversion of (S)-N-methylcoclaurine	Papaver somniferum	?	-	?	89