EC Number   |
General Information |
Reference |
|---|
    4.1.1.29 | evolution |
CSAD is a member of the type II PLP-dependent amino acid decarboxylase carboxylase family |
746717 |
| 4.1.1.29 | malfunction |
the mutant Undec1A-1180 has 5.62fold highxader specific activity than wild-type Undec1A |
747823 |
| 4.1.1.29 | metabolism |
CSAD gene is the key enzyme in the pathway of taurine biosynthesis |
749353 |
| 4.1.1.29 | more |
structure homology modelling and molecular docking, overview |
747823 |
| 4.1.1.29 | physiological function |
CSAD gene is the key enzyme in the pathway of taurine biosynthesis |
749353 |
| 4.1.1.29 | physiological function |
CSD is the rate-limiting enzyme of taurine biosynthesis |
746938, 747823 |
| 4.1.1.29 | physiological function |
cysteine sulfinate decarboxylase is the main rate-limiting enzyme for taurine synthesis |
701655 |
| 4.1.1.29 | physiological function |
cysteine sulfinic acid decarboxylase catalyzes the reaction of decarboxylation of cysteine sulfinic acid into hypotaurine. This step is considered as a rate-limiting step of taurine biosynthesis. Marine fish generally show low taurine synthesis activity |
746903 |
| 4.1.1.29 | physiological function |
knockdown of expression significantly reduces the embryonic taurine level, and the affected embryos have increased early mortality and cardiac anomalies |
726667 |
| 4.1.1.29 | physiological function |
the gills of Bathymodiolus septemdierum maintain high levels of expression of the CSAD gene regardless of ambient sulfide level and accumulate hypotaurine continuously to protect against sudden exposure to high level of sulfide. Since CSAD gene expression is observed in all the tissues examined, it is likely that hypotaurine is synthesized extensively in mussel tissues |
746717 |
