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Literature summary for 4.1.1.29 extracted from

  • Zhao, X.; Li, Q.; Meng, Q.; Yue, C.; Xu, C.
    Identification and expression of cysteine sulfinate decarboxylase, possible regulation of taurine biosynthesis in Crassostrea gigas in response to low salinity (2017), Sci. Rep., 7, 5505 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.1.29

Cloned(Commentary)

Cloned (Comment) Organism
gene CSAD1, Crassostrea gigas has two copies of CSAD, CgCSAD1 and CgCSAD2, DNA and amino acid sequence determination and analysis, quantitative real-time PCR enzyme expression analysis Crassostrea gigas
gene CSAD2, Crassostrea gigas has two copies of CSAD, CgCSAD1 and CgCSAD2, DNA and amino acid sequence determination and analysis, quantitative real-time PCR enzyme expression analysis Crassostrea gigas

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information the CSAD1 sequence contains no signal peptide Crassostrea gigas
-
-
additional information the CSAD2 sequence contains no signal peptide Crassostrea gigas
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-sulfino-L-alanine Crassostrea gigas
-
 hypotaurine + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Crassostrea gigas A0A221J366 CSAD1; has two copies of cysteine sulfinate decarboxylase (CSAD), CgCSAD1 and CgCSAD2, from two different wild populations Weihai (salinity 30) and Dongying (salinity 16) in 2015
-
Crassostrea gigas A0A221J378 CSAD2; has two copies of cysteine sulfinate decarboxylase (CSAD), CgCSAD1 and CgCSAD2, from two different wild populations Weihai (salinity 30) and Dongying (salinity 16) in 2015
-

Source Tissue

Source Tissue Comment Organism Textmining
adductor
-
 Crassostrea gigas
-
digestive gland
-
 Crassostrea gigas
-
gill
-
 Crassostrea gigas
-
gonad isozyme CSAD1 shows highest expression levels in gonads and hemolymph Crassostrea gigas
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gonad isozyme CSAD2 shows highest expression levels in gonads and hemolymph Crassostrea gigas
-
hemolymph isozyme CSAD1 shows highest expression levels in gonads and hemolymph Crassostrea gigas
-
hemolymph isozyme CSAD2 shows highest expression levels in gonads and hemolymph Crassostrea gigas
-
labial palp
-
 Crassostrea gigas
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mantle
-
 Crassostrea gigas
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additional information tissue-specific expression pattern of CSAD isozymes, overview. Expression levels of isozyme CSAD1 are higher compared to isozyme CSAD2 Crassostrea gigas
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-sulfino-L-alanine
-
 Crassostrea gigas hypotaurine + CO2
-
 ?

Subunits

Subunits Comment Organism
? x * 56110, sequence calculation Crassostrea gigas
? x * 63350, sequence calculation Crassostrea gigas

Synonyms

Synonyms Comment Organism
CgCSAD1
-
 Crassostrea gigas
CgCSAD2
-
 Crassostrea gigas
CSAD
-
 Crassostrea gigas
Cysteine sulfinate decarboxylase
-
 Crassostrea gigas

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Crassostrea gigas

Expression

Organism Comment Expression
Crassostrea gigas under low salinity treatment (0.8% and 1.5%) no correlation between the expression of CSAD and different populations is observed. Isoform CgCSAD2 does not show significantly altered expression additional information
Crassostrea gigas under low salinity treatment (0.8% and 1.5%) no correlation between the expression of CSAD and different populations is observed. Isoform CgCSAD1 expression increases significantly in groups treated for 24 h up

General Information

General Information Comment Organism
metabolism CSAD gene is the key enzyme in the pathway of taurine biosynthesis Crassostrea gigas
physiological function CSAD gene is the key enzyme in the pathway of taurine biosynthesis Crassostrea gigas