EC Number   |
Expression |
Reference |
|---|
    4.1.1.32 | down |
activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4alpha. Isonicotinamide decreases the level of mRNA for PEPCK-C |
704541 |
| 4.1.1.32 | down |
activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4alpha. Isonicotinamide decreases the level of mRNA for PEPCK-C with an IC50 of 2.3 mM |
704541 |
| 4.1.1.32 | down |
phenobarbital directly suppresses PEPCK gene expression in spherical hepatocytes on EHS-gel, but not in those on type I collagen. Phenobarbital strongly suppresses cAMP-dependent induction of PEPCK gene expression |
746970 |
| 4.1.1.32 | more |
there is no effect of fish meal and fish oil substitution on hepatic levels of mitochondrial PEPCK mRNA |
702944 |
| 4.1.1.32 | up |
after the stimulations with lipopolysaccharide, peptidoglycan, Vibrio splendidus and Vibrio anguillarum, PEPCK transcripts in hemocytes are significantly upregulated |
747633 |
| 4.1.1.32 | up |
higher expression levels under gluconeogenic conditions |
669085 |
| 4.1.1.32 | up |
the pck mRNA level is higher when cells are grown on lactose than on glucose |
715782 |
| 4.1.1.32 | up |
there is a significant increase of 85% in kidney PEPCK activity of diabetic rats 0.85 units/g tissue/min in comparison to the 0.46 units/g tissue/min of normal controls, treatment of diabetic animals with cinnamaldehyde and glibenclamide for 60 days prevents the increase in PEPCK levels |
703170 |
