EC Number |
Expression |
Reference |
---|
3.1.6.2 | down |
shikonin, an ingredient of Lithospermum erythrorhizon, down-regulates the expression and activity of steroid sulfatase in breast cancer cells |
703009 |
3.1.6.2 | down |
Shu-Gan-Liang-Xue decoction down-regulates the expression of steroid sulfatase genes in human breast carcinoma MCF-7 cells in a dose-dependent manner |
704857 |
3.1.6.2 | down |
trichostatin A treatment suppresses STS mRNA expression |
702979 |
3.1.6.2 | more |
STS activity and gene expression are decreased during differentiation in cells treated with osteogenic supplement containing dexamethasone. The NFkappaB activators lipopolysaccharide and phorbol myristate acetate increase STS expression in undifferentiated and differentiated MG-63 cells, while the NFkappaB inhibitor BAY-11-7082 partially blocks these responses |
751563 |
3.1.6.2 | up |
expression increases upon stimulation with decidualisation media |
751352 |
3.1.6.2 | up |
steroid sulfatase expression is upregulated in breast carcinomas |
716213 |