EC Number   |
Reaction |
Reference |
|---|
   2.1.1.220 | S-adenosyl-L-methionine + adenine58 in tRNA = S-adenosyl-L-homocysteine + N1-methyladenine58 in tRNA |
- |
- |
| 2.1.1.220 | S-adenosyl-L-methionine + adenine58 in tRNA = S-adenosyl-L-homocysteine + N1-methyladenine58 in tRNA |
TRM61 is the subunit that binds S-adenosyl-l-methionine and both subunits contribute to target tRNA binding, catalytic mechanism, overview |
718504 |
| 2.1.1.220 | S-adenosyl-L-methionine + adenine58 in tRNA = S-adenosyl-L-homocysteine + N1-methyladenine58 in tRNA |
two possible mechanisms for methyl transfer: (A) with deprotonation of the amino exocyclic group of the adenine ring and via the intermediate imino tautomer of m1A, (B) by direct transfer of the methyl, without intermediate, detailed overview |
-, 735777 |
