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Information on EC 2.1.1.220 - tRNA (adenine58-N1)-methyltransferase

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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.220 tRNA (adenine58-N1)-methyltransferase
IUBMB Comments
The enzyme specifically methylates adenine58 in tRNA. The methylation of A58 is critical for maintaining the stability of initiator tRNAMet in yeast .
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes
Synonyms
gcd14p, gcd10p, rv2118c, rv2118p, trm61p, trm6p, trna (m1a58) methyltransferase, m1a58 trna methyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + adenine58 in tRNA = S-adenosyl-L-homocysteine + N1-methyladenine58 in tRNA
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PATHWAY SOURCE
PATHWAYS
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