EC Number   |
Posttranslational Modification |
Reference |
|---|
    1.2.4.1 | side-chain modification |
- |
348983 |
| 1.2.4.1 | side-chain modification |
addition of pyruvate decreases enzyme phosphyrylation and inactivation, more than 2 mol phosphate are incorporated per tetramer, modification of arginine residues by 2,3-butanedione decreases activity and prevents phosphorylation, suggesting that substrate binding sites and regulatory sites are close together |
348984 |
| 1.2.4.1 | proteolytic modification |
cleavage of 29 amino acid long leader peptide from alpha subunit suggested from deduced protein sequence |
348923 |
| 1.2.4.1 | phosphoprotein |
during lactate consumption, component E1 subunuit alpha Ser293 and Ser300 phosphorylation levels are 33% higher compared to the phase of glucose excess. At the same time, the relative phosphorylation level of Ser232 increases steadily throughout the cultivation (66% increase overall) |
762973 |
| 1.2.4.1 | more |
enzyme from chloroplast is not regulated by phosphorylation/dephosphorylation |
348936 |
| 1.2.4.1 | phosphoprotein |
enzyme is subject to regulation by phosphorylation at residues S232, S293, S300 |
759082 |
| 1.2.4.1 | side-chain modification |
inactivated by phosphorylation |
348935, 348936 |
| 1.2.4.1 | phosphoprotein |
mitochondrial proteins, Pkp2 (Ygl059wp) and Ppp2 (Ycr079wp), are engaged in the regulation of the pyruvate dehydrogenase complex by affecting the phosphorylation state of subunit Pda1 |
759464 |
| 1.2.4.1 | more |
not regulated by phosphorylation/dephosphorylation |
348919, 348968 |
| 1.2.4.1 | side-chain modification |
phosphorylation of recombinant alpha2,beta2 tetramer, 3.25 phosphoryl groups per mol tetramer are incorporated, 50% phosphorylation within 10 min, only the alpha subunit is phosphorylated |
348983 |
