Literature summary for 1.2.4.1 extracted from

Nemerya, N.S.; Zemskova, M.A.; Nyukhalkina, I.A.; Khailova, L.S.
Chemical modification of the essential arginine residues of pyruvate dehydrogenase prevents its phosphorylation by kinase (1996), FEBS Lett., 394, 96-98.

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Organism

Organism	UniProt	Comment	Textmining
Pigeon	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
side-chain modification	addition of pyruvate decreases enzyme phosphyrylation and inactivation, more than 2 mol phosphate are incorporated per tetramer, modification of arginine residues by 2,3-butanedione decreases activity and prevents phosphorylation, suggesting that substrate binding sites and regulatory sites are close together	Pigeon

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Release 2023.1 (January 2023)