EC Number   |
Application |
Reference |
|---|
    3.5.5.7 | biotechnology |
enzyme can be recombinantly produced in high yield and at mild reaction conditions, the robust enzyme can be a suitable biocatalyst for industrial applications |
-, 654298 |
| 3.5.5.7 | environmental protection |
Candida guilliermondii UFMG-Y65 might be useful for the bioremediation of environments contaminated with nitriles |
-, 655149 |
| 3.5.5.7 | industry |
the enzyme is a potential candidate for industrial applications for biosynthesis of carboxylic acid |
757415 |
| 3.5.5.7 | industry |
the enzyme is a promising biocatalyst for mild nitrile hydrolysis |
-, 756271 |
| 3.5.5.7 | industry |
the enzyme is engineered for the commercial production of 3-hydroxyvaleric acid |
-, 712260 |
| 3.5.5.7 | industry |
the high chemical specificity and frequent enantioselectivity of nitrilases makes them attractive biocatalysts for the production of fine chemicals and pharmaceutical intermediates. Nitrilases are also used in the treatment of toxic industrial effluent and cyanide remediation |
-, 712260 |
| 3.5.5.7 | industry |
under optimized conditions, using the fed-batch reaction mode, total of 1050 mM 3-cyanopyridine is hydrolyzed completely in 20.8 h with eight substrate feedings, yielding 129.2 g/l production of nicotinic acid and thus showing a potential for industrial application |
756205 |
| 3.5.5.7 | synthesis |
an efficient, scaleable synthesis of ethyl (R)-4-cyano-3-hydroxybutyrate, a potential intermediate in the synthesis of Atorvastatin (Lipitor) involves nitrilase-catalyzed desymmetrization of 3-hydroxyglutaronitrile |
670463 |
| 3.5.5.7 | synthesis |
biotransformation of acrylonitrile by thermophilic nitrilase from Streptomyces sp. MTCC 7546. Enzyme converts nitriles to acids without the formation of amides. Immobilization of whole cells in agar-agar or beads allows for 25 cycles at 50°C with conversion of 71% of acrylonitrile to acid at 6 h and 100% conversion at 3 h by free cells |
699065 |
| 3.5.5.7 | synthesis |
Candida guilliermondii UFMG-Y65 and the isolated enzyme, respectively, might be useful for the bioproduction of amides and acids |
-, 655149 |
