Information on EC 3.5.5.7 - Aliphatic nitrilase

for references in articles please use BRENDA:EC3.5.5.7
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EC Tree
     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.5 In nitriles
                3.5.5.7 Aliphatic nitrilase
IUBMB Comments
Preferentially hydrolyses aliphatic nitriles, some of which are apparently not substrates for other known nitrilases (EC 3.5.5.1). Substrates include crotononitrile, acrylonitrile and glutaronitrile.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes
+
2
=
+
Synonyms
BjNIT3397, cyanoalanine hydratase/nitrilase, More, NIT, NIT1, Nit4, NitA, nitC1, nitC2, NitPf5, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
R-CN + 2 H2O = R-COOH + NH3
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