EC Number   |
Application |
Reference |
|---|
   2.3.1.194 | biotechnology |
the enzyme represents a potential target to increase the flux through the mevalonate pathway |
745496 |
| 2.3.1.194 | medicine |
histological changes, decreased steroid hormone concentrations and decreased cholesterol supply are observed in nicotine-treated fetal adrenals. The expression of genes regulating ketone metabolic process decreases in nicotine-treated fetal adrenals. Acetoacetyl-CoA synthetase (AACS), the enzyme utilizing ketones for cholesterol supply, displays decreased expression and increased DNA methylation in the proximal promoter of AACS |
737280 |
| 2.3.1.194 | synthesis |
nphT7 can be used to significantly increase the concentration of acetoacetyl-CoA in cells, eventually leading to the production of useful terpenoids and poly-3-hydroxybutyrate |
706551 |
| 2.3.1.194 | synthesis |
usage of the enzyme for recombinant high-level production of poly(3-hydroxybutyrate), P(3HB), in Escherichia coli and Corynebacterium glutamicum. P(3HB) is the natural aliphatic polyester that can be processed into a wide variety of consumer products, including plastics, films and fibers |
714539 |
