EC Number   |
Natural Substrates |
|---|
   3.2.1.207 | Glc2Man9GlcNAc2 + H2O |
- |
| 3.2.1.207 | GlcMan9GlcNAc2 + H2O |
- |
| 3.2.1.207 | more |
Catalyzes the hydrolysis of the inner two alpha-1,3-linked glucose residues present in all N-linked immature oligosaccharides, associates with and glycosylates the protein CD45, possible role in CD45 regulation |
| 3.2.1.207 | more |
deletion of the glucosidase II gene in Trypanosoma brucei reveals novel N-glycosylation mechanisms in the biosynthesis of variant surface glycoprotein |
| 3.2.1.207 | more |
endoplasmic reticulum glucosidase II is required for pathogenicity of Ustilago maydis |
| 3.2.1.207 | GlcMan9GlcNAc2 + H2O |
G2M9 |
| 3.2.1.207 | more |
glucosidase II is a glycan-processing enzyme that trims two alpha1,3-linked glucose residues from N-glycan on newly synthesized glycoproteins |
| 3.2.1.207 | more |
glucosidase II is a glycoprotein-processing enzyme that successively cleaves two alpha1,3-linked glucose residues from N-linked oligosaccharides in the endoplasmic reticulum |
| 3.2.1.207 | Glc2Man9GlcNAc2 (G2M9)-protein + H2O |
glucosidase II plays a key role in glycoprotein processing in the endoplasmic reticulum. This enzyme trims two alpha-1,3-linked glucose residues, Glcalpha1,3Glc (cleavage 1) and Glcalpha1,3Man (cleavage 2) from high-mannose type Glc2Man9GlcNAc2 (G2M9)-proteins. A crowded milieu that contains bovine serum albumin greatly enhances the second trimming step (cleavage 2), which deglucosylates Glc1Man9GlcNAc2, but not the first trimming step (cleavage 1), which removes the terminal glucose residue from Glc2Man9GlcNAc2 |
| 3.2.1.207 | Glc2Man9GlcNAc2 + H2O |
i.e. G1M9 |
