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Information on EC 3.2.1.207 - mannosyl-oligosaccharide alpha-1,3-glucosidase

for references in articles please use BRENDA:EC3.2.1.207
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IUBMB Comments
This eukaryotic enzyme cleaves off sequentially the two alpha-1,3-linked glucose residues from the Glc2Man9GlcNAc2 oligosaccharide precursor of immature N-glycosylated proteins.
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The enzyme appears in viruses and cellular organisms
Synonyms
alpha glucosidase II, alpha-glucosidase II, CTHT_0046400, CTHT_0064960, CWH41, endoplasmic reticulum glucosidase II, ER glucosidase II, G-II, GANAB, GAS2, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Glc2Man9GlcNAc2-[protein] + H2O = GlcMan9GlcNAc2-[protein] + beta-D-glucopyranose
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GlcMan9GlcNAc2-[protein] + H2O = Man9GlcNAc2-[protein] + beta-D-glucopyranose
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