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EC Number
Metals/Ions
Commentary
Reference
1.1.5.3
Ca2+
-
287818
1.1.5.3
Ca2+
0.7 mM required for half-maximal activation of activity with 2,6-dichlorophenolindophenol in euthyroid rats, 0.002 mM required for half-maximal activation of activity with vitamin K3 in euthyroid rats. Ca2+ causes an alteration in the conformation of the enzyme
287821
1.1.5.3
K+
20 mM NaCl or KCl required for maximal activity
287807
1.1.5.3
Na+
20 mM NaCl or KCl required for maximal activity
287807
1.1.5.3
Ca2+
activated by Ca2+
690606
,
695272
1.1.5.3
Ca2+
activates
287829
,
287831
,
740095
1.1.5.3
Cd2+
activates
740095
1.1.5.3
Mg2+
activates
287821
,
740095
1.1.5.3
Mn2+
activates
740095
1.1.5.3
Ca2+
causes a conformational change of both the soluble and membrane-embedded enzyme
287829
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