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EC Number
Localization
Commentary
GeneOntology No.
Reference
2.3.1.B41
chromatin
-
GO:0000785
AmiGO
QuickGO
758437
2.3.1.B41
cytoplasmic stress granule
SIRT6 translocates into the cytoplasm under stress and regulates formation as well as disassembly of stress granules
GO:0010494
AmiGO
QuickGO
730101
2.3.1.B41
intracellular
-
GO:0005622
AmiGO
QuickGO
756689
2.3.1.B41
mitochondrion
-
GO:0005739
AmiGO
QuickGO
-
,
756973
2.3.1.B41
mitotic spindle
Sirt6 partially colocalizes with mitotic spindles
GO:0072686
AmiGO
QuickGO
730527
2.3.1.B41
nucleolus
Sirt6 is enriched in the nucleolus in the G1 phase of the cell cycle, while S phase nucleoli are almost entirely free of Sirt6
GO:0005730
AmiGO
QuickGO
730527
2.3.1.B41
nucleosome
-
GO:0000786
AmiGO
QuickGO
755787
2.3.1.B41
nucleosome
SIRT6 activity is nucleosome dependent, and suggest that its binding to the nucleosome might convert it into an active structure
GO:0000786
AmiGO
QuickGO
730498
2.3.1.B41
nucleus
-
GO:0005634
AmiGO
QuickGO
755787
,
756392
,
756407
,
756672
,
756689
,
757236
,
757931
,
758437
2.3.1.B41
nucleus
during interphase, Sirt6 is mostly localized to the nucleus
GO:0005634
AmiGO
QuickGO
730527
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