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Literature summary for 2.3.1.B41 extracted from

  • Ardestani, P.M.; Liang, F.
    Sub-cellular localization, expression and functions of Sirt6 during the cell cycle in HeLa cells (2012), Nucleus, 3, 442-451.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.B41

Localization

Localization Comment Organism GeneOntology No. Textmining
mitotic spindle Sirt6 partially colocalizes with mitotic spindles Homo sapiens 72686
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nucleolus Sirt6 is enriched in the nucleolus in the G1 phase of the cell cycle, while S phase nucleoli are almost entirely free of Sirt6 Homo sapiens 5730
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nucleus during interphase, Sirt6 is mostly localized to the nucleus Homo sapiens 5634
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Organism

Organism UniProt Comment Textmining
Homo sapiens Q8N6T7
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-

Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
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 Homo sapiens
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Synonyms

Synonyms Comment Organism
SIRT6
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 Homo sapiens
sirtuin 6
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 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens during mitosis, the Sirt6 expression level is increased up

General Information

General Information Comment Organism
metabolism cells overexpressing Sirt6 have a lower proliferation rate with a lower percentage of cells in mitosis, roles for Sirt6 in the nucleolus and in the mitotic phase of the cell cycle Homo sapiens