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EC Number
Inhibitors
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Structure
1.14.11.68
GSK-J4
both the mRNA and protein levels of mPR3 are significantly reduced compared to controls
1.14.11.68
GSK-J4
specific inhibitor, application dramatically suppresses Th17 cell differentiation in vitro
1.14.11.68
GSK-J4
specific inhibitor of the H3K27me3 histone demethylases UTX and JMJD3, inhibits herpes simplex virus HSV-1 reactivation from sensory neurons in vitro; specific inhibitor of the H3K27me3 histone demethylases UTX and JMJD3, inhibits herpes simplex virus HSV-1 reactivation from sensory neurons in vitro
1.14.11.68
GSKJ4
inhibitor is active against native and temozolomide-resistant glioblastoma cells, albeit at at a lower effcacy than JIB 04, inhibitor of lysine demethylase KDM5A,
EC 1.14.11.67
. GSK J4 and JIB 04 strongly synergize and are a potent combination against temozolomide-resistant glioblastoma cells. GSK J4 does not synergize with temozolomide
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