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3-phenylacryloyl-CoA + shikimate
CoA + 3-phenylacryloylshikimate
-
-
-
-
?
4-coumaroyl-CoA + 2,3-dihydroxybenzoate
CoA + 3-O-(4-coumaroyl)oxy-2-hydroxybenzoate
4-coumaroyl-CoA + 2,3-dihydroxybenzoate
CoA + ?
Coleus scutellarioides
-
-
-
?
4-coumaroyl-CoA + 3,4-dihydroxybenzoate
CoA + 3-O-(4-coumaroyl)oxy-4-hydroxybenzoate
4-coumaroyl-CoA + 3-aminobenzoate
CoA + 3-N-(4-coumaroyl)aminobenzoate
4-coumaroyl-CoA + 3-aminobenzoate
CoA + ?
Coleus scutellarioides
-
-
-
?
4-coumaroyl-CoA + 3-hydroxyanthranilate
CoA + 3-(4-coumaroyl)oxyanthranilate
4-coumaroyl-CoA + 3-hydroxybenzoate
CoA + 3-(4-coumaroyl)oxybenzoate
Coleus scutellarioides
-
-
-
?
4-coumaroyl-CoA + 3-hydroxybenzoate
CoA + 3-O-(4-coumaroyl)oxy-benzoate
4-coumaroyl-CoA + 5-hydroxyanthranilate
CoA + 5-(4-coumaroyl)oxyanthranilate
4-coumaroyl-CoA + catechol
CoA + 1-(4-coumaroyl)catechol
low affinity substrate
-
-
?
4-coumaroyl-CoA + catechol
CoA + 1-O-(4-coumaroyl)catechol
-
-
-
?
4-coumaroyl-CoA + gentisate
CoA + 5-O-(4-coumaroyl)gentisate
4-coumaroyl-CoA + glycerol
CoA + 2-O-(4-coumaroyl)glycerol + 1-O-(4-coumaroyl)glycerol
-
-
-
-
?
4-coumaroyl-CoA + hydroquinone
CoA + 1-(4-coumaroyl)hydroquinone
low affinity substrate
-
-
?
4-coumaroyl-CoA + hydroquinone
CoA + 1-O-(4-coumaroyl)hydroquinone
-
-
-
?
4-coumaroyl-CoA + L-malate
CoA + 2-O-(4-coumaryl)-L-malate
-
-
-
?
4-coumaroyl-CoA + quinate
CoA + 4-coumaroylquinate
4-coumaroyl-CoA + quinate
CoA + 5-(4-coumaroyl)quinate
-
-
-
-
?
4-coumaroyl-CoA + quinate
CoA + 5-O-(4-coumaroyl)quinate
4-coumaroyl-CoA + shikimate
CoA + 4-coumaroylshikimate
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
caffeoyl-CoA + 2,3-dihydroxybenzoate
CoA + ?
Coleus scutellarioides
-
-
-
?
caffeoyl-CoA + 3-aminobenzoate
CoA + ?
Coleus scutellarioides
-
-
-
?
caffeoyl-CoA + 3-hydroxyanthranilate
CoA + 3-caffeoyloxyanthranilate
Coleus scutellarioides
-
-
-
?
caffeoyl-CoA + 3-hydroxybenzoate
CoA + 3-caffeoyloxybenzoate
Coleus scutellarioides
-
-
-
?
caffeoyl-CoA + glycerol
CoA + ?
-
-
-
-
?
caffeoyl-CoA + L-malate
CoA + 2-O-caffeoyl-L-malate
-
-
-
?
caffeoyl-CoA + quinate
CoA + 5-caffeoylquinate
-
-
-
r
caffeoyl-CoA + quinate
CoA + 5-O-caffeoylquinate
reaction of EC 2.3.1.99
-
-
r
caffeoyl-CoA + quinate
CoA + caffeoylquinate
caffeoyl-CoA + shikimate
CoA + 5-caffeoylshikimate
caffeoyl-CoA + shikimate
CoA + 5-O-caffeoylshikimate
cinnamoyl-CoA + 2,3-dihydroxybenzoate
CoA + ?
Coleus scutellarioides
-
-
-
?
cinnamoyl-CoA + 3-aminobenzoate
CoA + ?
Coleus scutellarioides
-
-
-
?
cinnamoyl-CoA + 3-hydroxyanthranilate
CoA + 3-cinnamoyloxyanthranilate
Coleus scutellarioides
-
-
-
?
cinnamoyl-CoA + 3-hydroxybenzoate
CoA + 3-cinnamoyloxybenzoate
Coleus scutellarioides
-
-
-
?
cinnamoyl-CoA + shikimate
CoA + 5-O-cinnamoylshikimate
CoA + 5-O-caffeoylquinate
caffeoyl-CoA + quinate
reaction of EC 2.3.1.99
-
-
r
feruloyl-CoA + 2,3-dihydroxybenzoate
CoA + ?
Coleus scutellarioides
-
-
-
?
feruloyl-CoA + 3-aminobenzoate
CoA + ?
Coleus scutellarioides
-
-
-
?
feruloyl-CoA + 3-hydroxyanthranilate
CoA + 3-feruloyloxyanthranilate
Coleus scutellarioides
-
-
-
?
feruloyl-CoA + 3-hydroxybenzoate
CoA + 3-feruloyloxybenzoate
Coleus scutellarioides
-
-
-
?
feruloyl-CoA + glycerol
CoA + ?
-
-
-
-
?
feruloyl-CoA + shikimate
CoA + 5-O-feruloylshikimate
sinapoyl-CoA + 3-hydroxyanthranilate
CoA + 3-sinapoyloxyanthranilate
Coleus scutellarioides
-
-
-
r
sinapoyl-CoA + shikimate
CoA + 5-O-sinapoylshikimate
additional information
?
-
4-coumaroyl-CoA + 2,3-dihydroxybenzoate
CoA + 3-O-(4-coumaroyl)oxy-2-hydroxybenzoate
-
-
-
?
4-coumaroyl-CoA + 2,3-dihydroxybenzoate
CoA + 3-O-(4-coumaroyl)oxy-2-hydroxybenzoate
low affinity substrate
-
-
?
4-coumaroyl-CoA + 3,4-dihydroxybenzoate
CoA + 3-O-(4-coumaroyl)oxy-4-hydroxybenzoate
i.e. protocatechuate
-
-
?
4-coumaroyl-CoA + 3,4-dihydroxybenzoate
CoA + 3-O-(4-coumaroyl)oxy-4-hydroxybenzoate
i.e. protocatechuate
-
-
?
4-coumaroyl-CoA + 3-aminobenzoate
CoA + 3-N-(4-coumaroyl)aminobenzoate
-
-
-
?
4-coumaroyl-CoA + 3-aminobenzoate
CoA + 3-N-(4-coumaroyl)aminobenzoate
low affinity substrate
-
-
?
4-coumaroyl-CoA + 3-hydroxyanthranilate
CoA + 3-(4-coumaroyl)oxyanthranilate
-
-
-
?
4-coumaroyl-CoA + 3-hydroxyanthranilate
CoA + 3-(4-coumaroyl)oxyanthranilate
Coleus scutellarioides
-
-
-
?
4-coumaroyl-CoA + 3-hydroxyanthranilate
CoA + 3-(4-coumaroyl)oxyanthranilate
-
-
-
?
4-coumaroyl-CoA + 3-hydroxybenzoate
CoA + 3-O-(4-coumaroyl)oxy-benzoate
-
-
-
?
4-coumaroyl-CoA + 3-hydroxybenzoate
CoA + 3-O-(4-coumaroyl)oxy-benzoate
low affinity substrate
-
-
?
4-coumaroyl-CoA + 5-hydroxyanthranilate
CoA + 5-(4-coumaroyl)oxyanthranilate
-
-
-
?
4-coumaroyl-CoA + 5-hydroxyanthranilate
CoA + 5-(4-coumaroyl)oxyanthranilate
low affinity substrate
-
-
?
4-coumaroyl-CoA + gentisate
CoA + 5-O-(4-coumaroyl)gentisate
-
-
-
?
4-coumaroyl-CoA + gentisate
CoA + 5-O-(4-coumaroyl)gentisate
low affinity substrate
-
-
?
4-coumaroyl-CoA + quinate
CoA + 4-coumaroylquinate
-
-
-
-
?
4-coumaroyl-CoA + quinate
CoA + 4-coumaroylquinate
-
-
-
r
4-coumaroyl-CoA + quinate
CoA + 4-coumaroylquinate
-
-
-
r
4-coumaroyl-CoA + quinate
CoA + 4-coumaroylquinate
-
-
-
-
?
4-coumaroyl-CoA + quinate
CoA + 4-coumaroylquinate
-
preferred substrate is shikimate
-
-
?
4-coumaroyl-CoA + quinate
CoA + 4-coumaroylquinate
-
-
-
-
?
4-coumaroyl-CoA + quinate
CoA + 4-coumaroylquinate
reaction products are detected when quinic acid is used as an acceptor, although the amount of product formed is less than 2% of that formed when shikimic acid serves as the acceptor
-
-
?
4-coumaroyl-CoA + quinate
CoA + 5-O-(4-coumaroyl)quinate
-
-
-
?
4-coumaroyl-CoA + quinate
CoA + 5-O-(4-coumaroyl)quinate
-
-
-
?
4-coumaroyl-CoA + quinate
CoA + 5-O-(4-coumaroyl)quinate
low activity towards quinate
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 4-coumaroylshikimate
-
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 4-coumaroylshikimate
-
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 4-coumaroylshikimate
-
recombinant HCT shows substrate-specificity towards shikimic acid in contrast to hydroxycinnamoyl-CoA quinate transferase, HQT, EC 2.3.1.99
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 4-coumaroylshikimate
-
preferred substrate is shikimate
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
biosynthetic pathway of hydroxycinnamic acid glucaric acid
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
-
-
r
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
hydroxycinnamic acid-shikimate ester biosynthesis
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
Coleus scutellarioides
-
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
Coleus scutellarioides
preferred substrate for HST with shikimate as acceptor substrate is 4-coumaroyl-CoA
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
-
product determination
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
shikimate cannot be replaced by quinate
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
-
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
-
r
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
enzyme appears to play a critical role in the phenylpropanoid pathway, both upstream and downstream of the 3-hydroxylation step
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
enzyme appears to play a critical role in the phenylpropanoid pathway, both upstream and downstream of the 3-hydroxylation step
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
-
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
best substrate
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
-
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
hydroxycinnamic acid-shikimate ester biosynthesis
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
best substrate
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
-
-
?
4-coumaroyl-CoA + shikimate
CoA + 5-O-(4-coumaroyl)shikimate
-
-
product determination
-
?
caffeoyl-CoA + quinate
CoA + caffeoylquinate
-
-
-
r
caffeoyl-CoA + quinate
CoA + caffeoylquinate
reaction products are detected when quinic acid is used as an acceptor, although the amount of product formed is less than 2% of that formed when shikimic acid serves as the acceptor
-
-
?
caffeoyl-CoA + shikimate
CoA + 5-caffeoylshikimate
-
-
-
r
caffeoyl-CoA + shikimate
CoA + 5-caffeoylshikimate
-
-
-
?
caffeoyl-CoA + shikimate
CoA + 5-caffeoylshikimate
-
-
-
?
caffeoyl-CoA + shikimate
CoA + 5-caffeoylshikimate
-
-
-
r
caffeoyl-CoA + shikimate
CoA + 5-O-caffeoylshikimate
-
-
-
-
?
caffeoyl-CoA + shikimate
CoA + 5-O-caffeoylshikimate
Coleus scutellarioides
-
-
-
r
caffeoyl-CoA + shikimate
CoA + 5-O-caffeoylshikimate
-
-
-
?
caffeoyl-CoA + shikimate
CoA + 5-O-caffeoylshikimate
-
-
-
r
caffeoyl-CoA + shikimate
CoA + 5-O-caffeoylshikimate
-
the activity is 100fold lower than the activity with coumaroyl-CoA
-
-
?
caffeoyl-CoA + shikimate
CoA + 5-O-caffeoylshikimate
-
-
-
-
?
caffeoyl-CoA + shikimate
CoA + 5-O-caffeoylshikimate
-
-
-
-
?
caffeoyl-CoA + shikimate
CoA + 5-O-caffeoylshikimate
-
-
-
-
?
caffeoyl-CoA + shikimate
CoA + 5-O-caffeoylshikimate
-
condensation at 52% the rate of the reaction with p-coumaroyl-CoA
-
-
?
caffeoyl-CoA + shikimate
CoA + 5-O-caffeoylshikimate
-
-
-
?
cinnamoyl-CoA + shikimate
CoA + 5-O-cinnamoylshikimate
Coleus scutellarioides
very low activity
-
-
r
cinnamoyl-CoA + shikimate
CoA + 5-O-cinnamoylshikimate
-
-
-
-
?
feruloyl-CoA + shikimate
CoA + 5-O-feruloylshikimate
-
-
-
-
?
feruloyl-CoA + shikimate
CoA + 5-O-feruloylshikimate
Coleus scutellarioides
-
-
-
r
feruloyl-CoA + shikimate
CoA + 5-O-feruloylshikimate
-
-
-
-
?
feruloyl-CoA + shikimate
CoA + 5-O-feruloylshikimate
-
-
-
?
feruloyl-CoA + shikimate
CoA + 5-O-feruloylshikimate
-
-
-
r
feruloyl-CoA + shikimate
CoA + 5-O-feruloylshikimate
-
-
-
-
?
feruloyl-CoA + shikimate
CoA + 5-O-feruloylshikimate
-
-
-
-
?
feruloyl-CoA + shikimate
CoA + 5-O-feruloylshikimate
-
-
-
?
feruloyl-CoA + shikimate
CoA + 5-O-feruloylshikimate
-
-
-
-
?
feruloyl-CoA + shikimate
CoA + 5-O-feruloylshikimate
-
condensation at 22% the rate of the reaction with p-coumaroyl-CoA
-
-
?
sinapoyl-CoA + shikimate
CoA + 5-O-sinapoylshikimate
Coleus scutellarioides
very low activity
-
-
r
sinapoyl-CoA + shikimate
CoA + 5-O-sinapoylshikimate
-
condensation at 29% the rate of the reaction with p-coumaroyl-CoA
-
-
?
additional information
?
-
-
no substrates are 1-hydroxycinnamoyl glucose
-
-
?
additional information
?
-
-
no substrate: cinnamoyl-CoA, L-malate, D(+)-malate, L(+)-tartrate, m-tartrate, citrate, glucose, UDP-glucose, myo-inositol, tyramine, agmatine
-
-
?
additional information
?
-
HCT has a preference for shikimic acid over quinic acid, substrate specifities of the HCT key enzyme, overview
-
-
?
additional information
?
-
-
HCT has a preference for shikimic acid over quinic acid, substrate specifities of the HCT key enzyme, overview
-
-
?
additional information
?
-
Coleus scutellarioides
substrate specificity of recombinant HST: no activity with quinate and anthranilate, and tyramine, tryptamine, serotonin, dopamine, DOPA, 2-phenethylamine, phenol, as acceptors
-
-
?
additional information
?
-
-
the enzyme is involved in the phenylpropanoid pathway and the biosynthesis of curcuminoids and in lignification, the enzyme activity is modulated in plants as a mechanism to control production of specific metabolites, overview
-
-
?
additional information
?
-
-
the enzyme is part of the monolignol pathway, enzymes of this pathway are individually downregulated resulting in compositional changes in lignin and wall-bound hydroxycinnamic acids, modelling, enzyme expression and metabolism, regulation, overview
-
-
?
additional information
?
-
no substrate: anthranilate, glucose, malate, tyramine, spermidine, spermine, putrescine, agmatine, benzyl alcohol
-
-
?
additional information
?
-
-
no substrate: anthranilate, glucose, malate, tyramine, spermidine, spermine, putrescine, agmatine, benzyl alcohol
-
-
?
additional information
?
-
-
no determination of the in vivo substrate
-
-
?
additional information
?
-
-
OsHCT4 mediates the trans-esterification of glycerol as well as shikimic acid in the presence of hydroxycinnamoyl-CoA in vitro, reaction product structure determination by NMR
-
-
?
additional information
?
-
-
HCT mediates formation of hydroxycinnamoylquinnate or hydroxycinnamoylshikimate
-
-
?
additional information
?
-
-
in vitro recombinant PeHCT shows substrate-specificity towards shikimic acid
-
-
?
additional information
?
-
-
no substrate: cinnamoyl-CoA, L-malate, D(+)-malate, L(+)-tartrate, m-tartrate, citrate, glucose, UDP-glucose, myo-inositol, tyramine, agmatine
-
-
?
additional information
?
-
-
1-hydroxycinnamoyl glucose esters, gluconolactone, galactonate, glucuronate, ascorbate, malate, m-tartrate
-
-
?
additional information
?
-
no reaction products are detected when HCT1 and either hydroxycinnamoyl-CoA derivative are incubated with malic acid, Glc, or L-DOPA as acceptor
-
-
?
additional information
?
-
no reaction products are detected when HCT1 and either hydroxycinnamoyl-CoA derivative are incubated with malic acid, Glc, or L-DOPA as acceptor
-
-
?
additional information
?
-
no reaction products are detected when HCT1 and either hydroxycinnamoyl-CoA derivative are incubated with malic acid, Glc, or L-DOPA as acceptor
-
-
?
additional information
?
-
no reaction products are detected when shikimic acid, quinic acid, Glc, or L-DOPA is used as an acceptor
-
-
?
additional information
?
-
no reaction products are detected when shikimic acid, quinic acid, Glc, or L-DOPA is used as an acceptor
-
-
?
additional information
?
-
no reaction products are detected when shikimic acid, quinic acid, Glc, or L-DOPA is used as an acceptor
-
-
?
additional information
?
-
-
the enzyme is involved in the phenylpropanoid pathway and the biosynthesis of curcuminoids and in lignification, the enzyme activity is modulated in plants as a mechanism to control production of specific metabolites, overview
-
-
?
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0.188 - 0.699
2,3-Dihydroxybenzoate
1.48
3,4-dihydroxybenzoate
pH 7.5, 30°C
2.404
3-aminobenzoate
Coleus scutellarioides
pH 7.0, 30°C, with 4-coumaroyl-CoA
0.449 - 0.83
3-Hydroxyanthranilate
0.733 - 1.677
3-hydroxybenzoate
1.1
3-phenylacryloyl-CoA
-
-
0.0015 - 14.3
4-coumaroyl-CoA
0.119
4-coumaroylshikimate
-
-
0.227 - 0.265
5-O-caffeoylquinate
0.0051 - 30.5
caffeoyl-CoA
0.0265
cinnamoyl-CoA
Coleus scutellarioides
pH 7.0, 30°C, with shikimate
0.0051 - 55.5
feruloyl-CoA
0.0859
glycerol
-
pH 7.5, 37°C, with feruloyl-CoA
0.02
sinapoyl-CoA
Coleus scutellarioides
pH 7.0, 30°C, with shikimate
additional information
additional information
-
0.188
2,3-Dihydroxybenzoate
Coleus scutellarioides
pH 7.0, 30°C, with 4-coumaroyl-CoA
0.699
2,3-Dihydroxybenzoate
Coleus scutellarioides
pH 7.0, 30°C, with caffeoyl-CoA
0.449
3-Hydroxyanthranilate
Coleus scutellarioides
pH 7.0, 30°C, with caffeoyl-CoA
0.473
3-Hydroxyanthranilate
Coleus scutellarioides
pH 7.0, 30°C, with 4-coumaroyl-CoA
0.83
3-Hydroxyanthranilate
pH 7.5, 30°C
0.733
3-hydroxybenzoate
Coleus scutellarioides
pH 7.0, 30°C, with caffeoyl-CoA
1.677
3-hydroxybenzoate
Coleus scutellarioides
pH 7.0, 30°C, with 4-coumaroyl-CoA
0.0015
4-coumaroyl-CoA
Coleus scutellarioides
pH 7.0, 30°C, with 3-hydroxybenzoate
0.0031
4-coumaroyl-CoA
Coleus scutellarioides
pH 7.0, 30°C, with 2,3-dihydroxybenzoate
0.0043
4-coumaroyl-CoA
Coleus scutellarioides
pH 7.0, 30°C, with shikimate
0.00813
4-coumaroyl-CoA
-
pH 8.0, 37°C, recombinant GST-tagged enzyme, with shikimate
0.0086
4-coumaroyl-CoA
-
-
0.00964
4-coumaroyl-CoA
-
pH 8.0, 37°C, recombinant GST-tagged enzyme, with quinate
0.0185
4-coumaroyl-CoA
Coleus scutellarioides
pH 7.0, 30°C, with 3-aminobenzoate
0.022
4-coumaroyl-CoA
Coleus scutellarioides
pH 7.0, 30°C, with 3-hydroxyanthranilate
0.024
4-coumaroyl-CoA
-
-
0.0295
4-coumaroyl-CoA
pH 6.5, 30°C
0.0378
4-coumaroyl-CoA
pH 6.5, 30°C
0.0601
4-coumaroyl-CoA
-
pH 7.5, 37°C, with glycerol
8.13
4-coumaroyl-CoA
-
with shikimate, pH 8.0, 37°C
9.64
4-coumaroyl-CoA
-
with quinate, pH 8.0, 37°C
0.227
5-O-caffeoylquinate
cosubstrate caffeoyl-CoA, pH 7.0, 25°C
0.265
5-O-caffeoylquinate
cosubstrate caffeoyl-CoA, pH 7.0, 25°C
0.0051
caffeoyl-CoA
Coleus scutellarioides
pH 7.0, 30°C, with 3-hydroxybenzoate
0.0088
caffeoyl-CoA
Coleus scutellarioides
pH 7.0, 30°C, with shikimate
0.0118
caffeoyl-CoA
Coleus scutellarioides
pH 7.0, 30°C, with 2,3-dihydroxybenzoate
0.0538
caffeoyl-CoA
Coleus scutellarioides
pH 7.0, 30°C, with 3-hydroxyanthranilate
0.102
caffeoyl-CoA
-
pH 7.5, 37°C, with glycerol
0.421
caffeoyl-CoA
cosubstrate quinate, pH 7.0, 25°C
1.296
caffeoyl-CoA
cosubstrate quinate, pH 7.0, 25°C
0.019
CoA
cosubstrate caffeoyl-CoA, pH 7.0, 25°C
0.107
CoA
cosubstrate caffeoyl-CoA, pH 7.0, 25°C
0.0051
feruloyl-CoA
Coleus scutellarioides
pH 7.0, 30°C, with shikimate
0.0721
feruloyl-CoA
-
pH 7.5, 37°C, with glycerol
0.00582
quinate
-
pH 8.0, 37°C, recombinant GST-tagged enzyme, with 4-coumaroyl-CoA
0.121
quinate
pH 6.5, 30°C
0.13
quinate
cosubstrate caffeoyl-CoA, pH 7.0, 25°C
0.133
quinate
pH 6.5, 30°C
0.444
quinate
cosubstrate caffeoyl-CoA, pH 7.0, 25°C
5.82
quinate
-
with 4-coumaroyl-CoA, pH 8.0, 37°C
0.0009
shikimate
-
pH 8.0, 37°C, recombinant GST-tagged enzyme, with 4-coumaroyl-CoA
0.0102
shikimate
pH 6.5, 30°C
0.0114
shikimate
pH 6.5, 30°C
0.0631
shikimate
mutant Y40A, pH 6.5, temperature not specified in the publication
0.153
shikimate
wild-type, pH 6.5, temperature not specified in the publication
0.1558
shikimate
-
pH 7.5, 37°C, with feruloyl-CoA
0.332
shikimate
Coleus scutellarioides
pH 7.0, 30°C, with 4-coumaroyl-CoA
0.59
shikimate
-
with 4-coumaroyl-CoA
0.678
shikimate
mutant S38A, pH 6.5, temperature not specified in the publication
0.699
shikimate
pH 7.5, 30°C
0.9
shikimate
-
with 4-coumaroyl-CoA, pH 8.0, 37°C
2.235
shikimate
Coleus scutellarioides
pH 7.0, 30°C, with cinnamoyl-CoA
2.473
shikimate
cosubstrate caffeoyl-CoA, pH 7.0, 25°C
2.69
shikimate
cosubstrate caffeoyl-CoA, pH 7.0, 25°C
6.495
shikimate
Coleus scutellarioides
pH 7.0, 30°C, with caffeoyl-CoA
22.38
shikimate
Coleus scutellarioides
pH 7.0, 30°C, with feroyl-CoA
26.13
shikimate
Coleus scutellarioides
pH 7.0, 30°C, with sinapoyl-CoA
83
shikimate
-
with caffeoyl-CoA
additional information
additional information
-
kinetics, overview
-
additional information
additional information
Coleus scutellarioides
kinetics, overview
-
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Strack, D.; Keller, H.; Weissenbck, G.
Enzymatic synthesis of hydroxycinnamic acid esters of sugar acids and hydroaromatic acids by protein preparations from rye (Secale cereale) primary leaves
J. Plant Physiol.
131
61-73
1987
Secale cereale
-
brenda
Strack, D.; Gross, W.; Heilemann, J.; Keller, H.; Ohm, S.
Enzymic synthesis of hydroxycinnamic acid esters of glucaric acid and hydroaromatic acids from the respective 1-O-hydroxycinnamoylglucoside and hydroxycinnamoyl-Coenzyme A thioester as acyldonors with a protein preparation from Cestrum elegans leaves
Z. Naturforsch. C
43c
32-36
1987
Cestrum elegans
-
brenda
Ulbrich, B.; Zenk, M.H.
Partial purification and properties of p-hydroxycinnamoyl-CoA: shikimate-p-hydroxy-cinnamoyl transferase from higher plants
Phytochemistry
19
1625-1629
1980
Cichorium endivia
-
brenda
Lotfy, L.; Fleuriet, A.; Macheix, J.J.
Partial purification and characterization of hydroxycinnamoyl CoA:transferase from apple and date fruits
Phytochemistry
31
767-772
1992
Phoenix dactylifera
-
brenda
Lotfy, S.; Fleuriet, A.; Macheix, J.J.
Hydroxycinnamoyl-CoA: transferases in higher plants. II. Characterization in Cichorium endivia and Raphanus sativus and comparison with other plants
Plant Physiol. Biochem.
32
355-363
1994
Cichorium endivia, Raphanus sativus
-
brenda
Lotfy, S.
Inactivation and kinetic characterization of hydroxycinnamoyl-CoA:hydroaromatic acid O-hydroxycinnamoyltransferases from Cichorium endivia and Phoenix dactylifera
Plant Physiol. Biochem.
33
423-431
1995
Phoenix dactylifera
-
brenda
Hohlfeld, M.; Veit, M.; Strack, D.
Hydroxycinnamoyltransferases Involved in the accumulation of caffeic acid esters in gametophytes and sporophytes of Equisetum arvense
Plant Physiol.
111
1153-1159
1996
Equisetum arvense
brenda
Gang, D.R.; Beuerle, T.; Ullmann, P.; Werck-Reichhart, D.; Pichersky, E.
Differential production of meta hydroxylated phenylpropanoids in sweet basil peltate glandular trichomes and leaves is controlled by the activities of specific acyltransferases and hydroxylases
Plant Physiol.
130
1536-1544
2002
Ocimum basilicum
brenda
Hoffmann, L.; Maury, S.; Martz, F.; Geoffroy, P.; Legrand, M.
Purification, cloning, and properties of an acyltransferase controlling shikimate and quinate ester intermediates in phenylpropanoid metabolism
J. Biol. Chem.
278
95-103
2003
Nicotiana tabacum (Q8GSM7), Nicotiana tabacum
brenda
Ramirez-Ahumada, M.d.e.l.C.; Timmermann, B.N.; Gang, D.R.
Biosynthesis of curcuminoids and gingerols in turmeric (Curcuma longa) and ginger (Zingiber officinale): identification of curcuminoid synthase and hydroxycinnamoyl-CoA thioesterases
Phytochemistry
67
2017-2029
2006
Zingiber officinale, Curcuma longa
brenda
Chen, F.; Srinivasa Reddy, M.S.; Temple, S.; Jackson, L.; Shadle, G.; Dixon, R.A.
Multi-site genetic modulation of monolignol biosynthesis suggests new routes for formation of syringyl lignin and wall-bound ferulic acid in alfalfa (Medicago sativa L.)
Plant J.
48
113-124
2006
Medicago sativa
brenda
Shadle, G.; Chen, F.; Reddy, M.S.; Jackson, L.; Nakashima, J.; Dixon, R.A.
Down-regulation of hydroxycinnamoyl CoA: Shikimate hydroxycinnamoyl transferase in transgenic alfalfa affects lignification, development and forage quality
Phytochemistry
68
1521-1529
2007
Medicago sativa
brenda
Wagner, A.; Ralph, J.; Akiyama, T.; Flint, H.; Phillips, L.; Torr, K.; Nanayakkara, B.; Te Kiri, L.
Exploring lignification in conifers by silencing hydroxycinnamoyl-CoA:shikimate hydroxycinnamoyltransferase in Pinus radiata
Proc. Natl. Acad. Sci. USA
104
11856-11861
2007
Pinus radiata
brenda
Comino, C.; Hehn, A.; Moglia, A.; Menin, B.; Bourgaud, F.; Lanteri, S.; Portis, E.
The isolation and mapping of a novel hydroxycinnamoyltransferase in the globe artichoke chlorogenic acid pathway
BMC Plant Biol.
9
30
2009
Cynara cardunculus (C3PTS8), Cynara cardunculus var. scolymus (C3PTS7), Cynara cardunculus var. scolymus
brenda
Sullivan, M.
A novel red clover hydroxycinnamoyl transferase has enzymatic activities consistent with a role in phaselic acid biosynthesis
Plant Physiol.
150
1866-1879
2009
Trifolium pratense (B6D7P1), Trifolium pratense (B6D7P2), Trifolium pratense (B6DQK4)
brenda
Lallemand, L.A.; McCarthy, J.G.; McSweeney, S.; McCarthy, A.A.
Purification, crystallization and preliminary X-ray diffraction analysis of a hydroxycinnamoyl-CoA shikimate/quinate hydroxycinnamoyltransferase (HCT) from Coffea canephora involved in chlorogenic acid biosynthesis
Acta Crystallogr. Sect. F
68
824-828
2012
Coffea canephora (A4ZKE4), Coffea canephora
brenda
Kim, B.; Kim, I.; Ahn, J.
Characterization of hydroxycinnamoyl-coenzyme A shikimate hydroxycinnamoyltransferase from Populus euramericana
J. Korean Soc. Appl. Biol. Chem.
54
817-821
2011
Populus x canadensis
-
brenda
Kim, I.; Kim, B.; Kim, M.; Ahn, J.
Characterization of hydroxycinnamoyltransferase from rice and its application for biological synthesis of hydroxycinnamoyl glycerols
Phytochemistry
76
25-31
2012
Oryza sativa
brenda
Sander, M.; Petersen, M.
Distinct substrate specificities and unusual substrate flexibilities of two hydroxycinnamoyltransferases, rosmarinic acid synthase and hydroxycinnamoyl-CoA:shikimate hydroxycinnamoyl-transferase, from Coleus blumei Benth.
Planta
233
1157-1171
2011
Coleus scutellarioides (E8ZAP2)
brenda
Eudes, A.; Pereira, J.H.; Yogiswara, S.; Wang, G.; Teixeira Benites, V.; Baidoo, E.E.; Lee, T.S.; Adams, P.D.; Keasling, J.D.; Loque, D.
Exploiting the substrate promiscuity of hydroxycinnamoyl-CoA:shikimate hydroxycinnamoyl transferase to reduce lignin
Plant Cell Physiol.
57
568-579
2016
Arabidopsis thaliana (Q9FI78), Panicum virgatum (R9RYW2), Panicum virgatum
brenda
Walker, A.M.; Hayes, R.P.; Youn, B.; Vermerris, W.; Sattler, S.E.; Kang, C.
Elucidation of the structure and reaction mechanism of sorghum hydroxycinnamoyltransferase and its structural relationship to other coenzyme a-dependent transferases and synthases
Plant Physiol.
162
640-651
2013
Sorghum bicolor (C5XXB7)
brenda
Wang, G.; He, Y.; Strauch, R.; Olukolu, B.; Nielsen, D.; Li, X.; Balint-Kurti, P.
Maize homologs of hydroxycinnamoyltransferase, a key enzyme in lignin biosynthesis, bind the nucleotide binding leucine-rich repeat rp1 proteins to modulate the defense response
Plant Physiol.
169
2230-2243
2015
Zea mays
brenda
Liu, Q.; Yao, L.; Xu, Y.; Cheng, H.; Wang, W.; Liu, Z.; Liu, J.; Cui, X.; Zhou, Y.; Ning, W.
In vitro evaluation of hydroxycinnamoyl CoA quinate hydroxycinnamoyl transferase expression and regulation in Taraxacum antungense in relation to 5-caffeoylquinic acid production
Phytochemistry
162
148-156
2019
Taraxacum antungense (A0A482LP01), Taraxacum antungense (A0A4D6ZMT8)
brenda
Ponniah, S.; Shang, Z.; Akbudak, M.; Srivastava, V.; Manoharan, M.
Down-regulation of hydroxycinnamoyl CoA shikimate hydroxycinnamoyl transferase, cinnamoyl CoA reductase, and cinnamyl alcohol dehydrogenase leads to lignin reduction in rice (Oryza sativa L. ssp. japonica cv. Nipponbare)
Plant Biotechnol. Rep.
11
17-27
2017
Oryza sativa Japonica Group
-
brenda
Krzyzaniak, Y.; Negrel, J.; Lemaitre-Guillier, C.; Clement, G.; Mouille, G.; Klinguer, A.; Trouvelot, S.; Heloir, M.C.; Adrian, M.
Combined enzymatic and metabolic analysis of grapevine cell responses to elicitors
Plant Physiol. Biochem.
123
141-148
2018
Vitis vinifera
brenda
Wu, Y.F.; Zhao, Y.; Liu, X.Y.; Gao, S.; Cheng, A.X.; Lou, H.X.
Isolation and functional characterization of hydroxycinnamoyltransferases from the liverworts Plagiochasma appendiculatum and Marchantia paleacea
Plant Physiol. Biochem.
129
400-410
2018
Marchantia paleacea (A0A346FEE5), Marchantia paleacea, Plagiochasma appendiculatum (A0A346FEE6), Plagiochasma appendiculatum
brenda