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Information on EC 1.2.1.98 - 2-hydroxy-2-methylpropanal dehydrogenase

for references in articles please use BRENDA:EC1.2.1.98

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IUBMB Comments

This bacterial enzyme is involved in the degradation pathways of the alkene 2-methylpropene and the fuel oxygenate methyl tert-butyl ether (MTBE), a widely occurring groundwater contaminant.

The enzyme appears in viruses and cellular organisms

Synonyms
hydroxyisobutyraldehyde dehydrogenase, mpdC, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-hydroxy-2-methylpropanal + NAD+ + H2O = 2-hydroxy-2-methylpropanoate + NADH + H+
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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Highest Expressing Human Cell Lines
Cell Line Links Gene Links