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Information on EC 1.14.19.10 - icosanoyl-CoA 5-desaturase

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IUBMB Comments
The enzyme, characterized from the plant Limnanthes douglasii (meadowfoam), is involved in the biosynthesis of (5Z)-icos-5-enoate, an unusual monounsaturated fatty acid that makes up to 60% of the total fatty acids in Limnanthes sp. seed oil. The enzyme only acts on saturated fatty acids.
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Word Map
  • 1.14.19.10
  • delta6
  • polyunsaturated
  • desaturases
  • arachidonic
  • desaturation
  • linoleic
  • elongase
  • stearoyl-coa
  • monounsaturated
  • mortierella
  • gamma-linolenic
  • hufas
  • eicosapentaenoic
  • alpha-linolenic
  • salar
  • eicosatrienoic
  • alpina
  • omega6
  • di-homo-gamma-linolenic
The expected taxonomic range for this enzyme is: Limnanthes alba subsp. alba
Synonyms
acyl-CoA DELTA5 desaturase, Delta-5 acyl-CoA desaturase, DELTA5 desaturase, DELTA5DS, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
icosanoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = (Z)-icos-5-enoyl-CoA + 2 ferricytochrome b5 + 2 H2O
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PATHWAY SOURCE
PATHWAYS
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