Ligand ferricytochrome b5

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Basic Ligand Information

Molecular Structure
Picture of ferricytochrome b5 (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C36H36FeN4O2
ferricytochrome b5
VIJMEYIOPTVQKA-PVPKHRJZSA-N
Synonyms:
(ferricytochrome c)-subunit, (ferrocytochrome c)-subunit, ferricytochrome-b5, ferricytochrome b-561, ferricytochrome b1, ferricytochrome b559/569, Ferricytochrome c-553, ferricytochrome c2, ferricytochrome c3, ferricytochrome c551i, ferricytochrome cL, ferrileghemoglobin, ferrocytochrome b-561, ferrocytochrome b1, ferrocytochrome b5, ferrocytochrome b559/569, ferrocytochrome c-553, ferrocytochrome c2, ferrocytochrome c3, ferrocytochrome c551i, ferrocytochrome c553, ferrocytochrome cL, ferroleghemoglobin

Show all pahtways known for Show all pathways known for ferricytochrome b5

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (103 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-lactate + ferricytochrome c-553 = pyruvate + ferrocytochrome c-553
show the reaction diagram
-
methanol + ferricytochrome c551i = formaldehyde + ferrocytochrome c551i
show the reaction diagram
-
L-(+)-ascorbate + ferricytochrome b5 = monodehydro-L(+)-ascorbate + ferrocytochrome b5
show the reaction diagram
-
H2 + ferricytochrome c3 = H+ + ferrocytochrome c3
show the reaction diagram
-
a phytoceramide + 2 ferrocytochrome b5 + O2 + 2 H+ = a (2'R)-2'-hydroxyphytoceramide + 2 ferricytochrome b5 + H2O
show the reaction diagram
-
24-methylene-24-dihydrocycloartenol + ferrocytochrome b5 + O2 = ?
show the reaction diagram
-
icosanoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = (Z)-icos-5-enoyl-CoA + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
linoleoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ = (9Z,11E,13Z)-octadeca-9,11,13-trienoyl-[glycerolipid] + ferricytochrome b5 + H2O
show the reaction diagram
-
alpha-linolenic acid + ferrocytochrome b5 + O2 + H+ = stearidonic acid + ferricytochrome b5 + H2O
show the reaction diagram
-
docosa-7,10,13,16,19-pentaenoic acid + 2 ferrocytochrome b5 + O2 + 2 H+ = docosa-4,7,10,13,16,19-hexaenoic acid + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
an oleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = a (9Z,12E)-octadeca-9,12-dienoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
myristic acid + 2 ferrocytochrome b5 + O2 + 2 H+ = (Z)-11-tetradecenoate + (E)-11-tetradecenoate + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
CO + H2O + ferrocytochrome b-561 = CO2 + H+ + ferricytochrome b-561
show the reaction diagram
-
pyruvate + ferricytochrome b1 + H2O = acetate + CO2 + ferrocytochrome b1
show the reaction diagram
-
2 ferricytochrome c2 + NADPH = 2 ferrocytochrome c2 + NADP+ + H+
show the reaction diagram
-
nitrite + ferrocytochrome c2 = NO + H2O + ferricytochrome c2
show the reaction diagram
-
trimethylamine N-oxide + (ferrocytochrome c)-subunit + H+ = trimethylamine + (ferricytochrome c)-subunit + H2O
show the reaction diagram
-
dimethyl sulfide + ferricytochrome c2 + H2O = dimethyl sulfoxide + ferrocytochrome c2
show the reaction diagram
-
thiosulfate + 2 ferrocytochrome c3 = sulfite + hydrogen sulfide + 2 ferricytochrome c3
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (96 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-lactate + ferricytochrome c-553 = pyruvate + ferrocytochrome c-553
show the reaction diagram
-
-
methanol + ferricytochrome c551i = formaldehyde + ferrocytochrome c551i
show the reaction diagram
-
-
L-(+)-ascorbate + ferricytochrome b5 = monodehydro-L(+)-ascorbate + ferrocytochrome b5
show the reaction diagram
-
-
H2 + ferricytochrome c3 = H+ + ferrocytochrome c3
show the reaction diagram
-
-
a phytoceramide + 2 ferrocytochrome b5 + O2 + 2 H+ = a (2'R)-2'-hydroxyphytoceramide + 2 ferricytochrome b5 + H2O
show the reaction diagram
-
-
icosanoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = (Z)-icos-5-enoyl-CoA + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
-
linoleoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ = (9Z,11E,13Z)-octadeca-9,11,13-trienoyl-[glycerolipid] + ferricytochrome b5 + H2O
show the reaction diagram
-
-
(4E)-sphing-4-enine ceramide + ferrocytochrome b5 + O2 + H+ = (4E,8E)-sphing-4,8-dienine ceramide + ferricytochrome b5 + H2O
show the reaction diagram
-
-
alpha-linolenic acid + ferrocytochrome b5 + O2 + H+ = stearidonic acid + ferricytochrome b5 + H2O
show the reaction diagram
-
-
docosa-7,10,13,16,19-pentaenoic acid + 2 ferrocytochrome b5 + O2 + 2 H+ = docosa-4,7,10,13,16,19-hexaenoic acid + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
-
an oleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = a (9Z,12E)-octadeca-9,12-dienoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
-
myristic acid + 2 ferrocytochrome b5 + O2 + 2 H+ = (Z)-11-tetradecenoate + (E)-11-tetradecenoate + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
-
CO + H2O + ferrocytochrome b-561 = CO2 + H+ + ferricytochrome b-561
show the reaction diagram
-
-
pyruvate + ferricytochrome b1 + H2O = acetate + CO2 + ferrocytochrome b1
show the reaction diagram
-
-
2 ferricytochrome c2 + NADPH = 2 ferrocytochrome c2 + NADP+ + H+
show the reaction diagram
-
-
nitrite + ferrocytochrome c2 = NO + H2O + ferricytochrome c2
show the reaction diagram
-
-
trimethylamine N-oxide + (ferrocytochrome c)-subunit + H+ = trimethylamine + (ferricytochrome c)-subunit + H2O
show the reaction diagram
-
-
dimethyl sulfide + ferricytochrome c2 + H2O = dimethyl sulfoxide + ferrocytochrome c2
show the reaction diagram
-
-
thiosulfate + 2 ferrocytochrome c3 = sulfite + hydrogen sulfide + 2 ferricytochrome c3
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (243 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
methanol + ferricytochrome c551i = formaldehyde + ferrocytochrome c551i
show the reaction diagram
-
sphinganine ceramide + 2 ferrocytochrome b5 + O2 + 2 H+ = 4-hydroxysphinganine ceramide + 2 ferricytochrome b5 + H2O
show the reaction diagram
-
icosanoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = (Z)-icos-5-enoyl-CoA + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
an oleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = a (9Z,12E)-octadeca-9,12-dienoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
myristic acid + 2 ferrocytochrome b5 + O2 + 2 H+ = (Z)-11-tetradecenoate + (E)-11-tetradecenoate + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
octadec-9-ynoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = (13Z)-octadecen-13-en-9-ynoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
formate + ferricytochrome c-553 = CO2 + ferrocytochrome c-553
show the reaction diagram
-
2 ferricytochrome c2 + NADPH = 2 ferrocytochrome c2 + NADP+ + H+
show the reaction diagram
-
2 ferricytochrome c2 + NADPH = 2 ferrocytochrome c2 + NADP+ + H+
show the reaction diagram
-
pyruvate + ferricytochrome b1 + H2O = acetate + CO2 + ferrocytochrome b1
show the reaction diagram
-
2 ferricytochrome c2 + NADPH = 2 ferrocytochrome c2 + NADP+ + H+
show the reaction diagram
-
2 ferricytochrome b5 + NADH = 2 ferrocytochrome b5 + NAD+ + H+
show the reaction diagram
-
2 ferricytochrome b5 + NADH = 2 ferrocytochrome b5 + NAD+ + H+
show the reaction diagram
-
thiosulfate + 2 ferrocytochrome c3 = sulfite + hydrogen sulfide + 2 ferricytochrome c3
show the reaction diagram
-
dimethyl sulfide + ferricytochrome c2 + H2O = dimethyl sulfoxide + ferrocytochrome c2
show the reaction diagram
-
thiosulfate + 2 ferrocytochrome c3 = sulfite + hydrogen sulfide + 2 ferricytochrome c3
show the reaction diagram
-
adenylyl sulfate + ferrocytochrome c3 = AMP + sulfite + ferricytochrome
show the reaction diagram
-
ubiquinol + ferricytochrome b-561 = ubiquinone + ferrocytochrome b-561
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (209 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
methanol + ferricytochrome c551i = formaldehyde + ferrocytochrome c551i
show the reaction diagram
-
-
ferrocytochrome c2 + H2O2 = ferricytochrome c2 + OH-
show the reaction diagram
-
-
sphinganine ceramide + 2 ferrocytochrome b5 + O2 + 2 H+ = 4-hydroxysphinganine ceramide + 2 ferricytochrome b5 + H2O
show the reaction diagram
-
-
icosanoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = (Z)-icos-5-enoyl-CoA + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
-
linoleoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ = (9Z,11E,13Z)-octadeca-9,11,13-trienoyl-[glycerolipid] + ferricytochrome b5 + H2O
show the reaction diagram
-
-
alpha-linolenic acid + ferrocytochrome b5 + O2 + H+ = stearidonic acid + ferricytochrome b5 + H2O
show the reaction diagram
-
-
an oleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = a (9Z,12E)-octadeca-9,12-dienoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
-
myristic acid + 2 ferrocytochrome b5 + O2 + 2 H+ = (Z)-11-tetradecenoate + (E)-11-tetradecenoate + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
-
octadec-9-ynoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = (13Z)-octadecen-13-en-9-ynoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
-
-
formate + ferricytochrome c-553 = CO2 + ferrocytochrome c-553
show the reaction diagram
-
2 ferricytochrome c2 + NADPH = 2 ferrocytochrome c2 + NADP+ + H+
show the reaction diagram
-
-
2 ferricytochrome c2 + NADPH = 2 ferrocytochrome c2 + NADP+ + H+
show the reaction diagram
-
-
pyruvate + ferricytochrome b1 + H2O = acetate + CO2 + ferrocytochrome b1
show the reaction diagram
-
-
2 ferricytochrome c2 + NADPH = 2 ferrocytochrome c2 + NADP+ + H+
show the reaction diagram
-
-
2 ferricytochrome b5 + NADH = 2 ferrocytochrome b5 + NAD+ + H+
show the reaction diagram
-
-
2 ferricytochrome b5 + NADH = 2 ferrocytochrome b5 + NAD+ + H+
show the reaction diagram
-
-
thiosulfate + 2 ferrocytochrome c3 = sulfite + hydrogen sulfide + 2 ferricytochrome c3
show the reaction diagram
-
-
dimethyl sulfide + ferricytochrome c2 + H2O = dimethyl sulfoxide + ferrocytochrome c2
show the reaction diagram
-
-
thiosulfate + 2 ferrocytochrome c3 = sulfite + hydrogen sulfide + 2 ferricytochrome c3
show the reaction diagram
-
-
ubiquinol + ferricytochrome b-561 = ubiquinone + ferrocytochrome b-561
show the reaction diagram
-
-

Enzyme Cofactor/Cosubstrate (11 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (48 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
17.7
-
-
239
-
pH 7.6, 37°C
2.35
-
pH 7.5, 30°C
5
-
-

KM Value (51 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0027
-
pH 7.6, 37°C
0.0176
-
pH 7.5, 30°C
0.037
-
-
0.021
-
in 220 mM Tris-HCl pH 8.0, 22°C

References & Links