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Information on EC 1.14.14.162 - flavanone 2-hydroxylase

for references in articles please use BRENDA:EC1.14.14.162
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IUBMB Comments
A cytochrome P-450 (heme thiolate) plant enzyme that catalyses the 2-hydroxylation of multiple flavanones such as (2S)-naringenin, (2S)-eriodictyol, (2S)-pinocembrin, and (2S)-liquiritigenin. The products are meta-stable and exist in an equilibrium with open forms such as 1-(4-hydroxyphenyl)-3-(2,4,6-trihydroxyphenyl)propane-1,3-dione.
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The enzyme appears in viruses and cellular organisms
Synonyms
(2S)-flavanone 2-hydroxylase, CYP93G2, F2H, licodione synthase, liquiritigenin,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (licodione-forming), LS, More, Os06g01250, OsF2H, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
a flavanone + [reduced NADPH-hemoprotein reductase] + O2 = a 2-hydroxyflavanone + [oxidized NADPH-hemoprotein reductase] + H2O
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