EC Explorer

7.1.1.11

ferredoxin—NAD⁺ oxidoreductase (H⁺-transporting)

2 reduced ferredoxin [iron-sulfur] cluster + NAD⁺ + H⁺ + 2 H⁺_{[side 1]} = 2 oxidized ferredoxin [iron-sulfur] cluster + NADH + 2 H⁺_{[side 2]}

Rnf complex (ambiguous), H⁺-translocating ferredoxin:NAD⁺ oxidoreductase

ferredoxin:NAD⁺ oxidoreductase (H⁺-transporting)

This iron-sulfur and flavin-containing electron transport complex, isolated from some anaerobic bacteria, couples the energy from reduction of NAD⁺ by ferredoxin to pumping protons out of the cell, generating a proton motive force across the cytoplasmic membrane. Most similar complexes pump sodium ions rather than protons [cf. EC 7.2.1.2, ferredoxin—NAD⁺ oxidoreductase (Na⁺-transporting)].

created 2021