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EC 2.7.11.20 Details
EC number
2.7.11.20
Accepted name
elongation factor 2 kinase
Reaction
ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate
Other name(s)
Ca/CaM-kinase III,
calmodulin-dependent protein kinase III,
CaM kinase III,
eEF2 kinase,
eEF2K,
EF2K,
STK19
Systematic name
ATP:[elongation factor 2] phosphotransferase
CAS registry number
116283-83-1
Comment
Requires Ca2+ and calmodulin for activity. The enzyme can also be phosphorylated by the catalytic subunit of EC 2.7.11.11, cAMP-dependent protein kinase. Elongation factor 2 is phosphorylated in several cell types in response to various growth factors, hormones and other stimuli that raise intracellular Ca2+ [1,2].
History
created 2005
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