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Information on EC 2.7.11.20 - elongation factor 2 kinase

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IUBMB Comments
Requires Ca2+ and calmodulin for activity. The enzyme can also be phosphorylated by the catalytic subunit of EC 2.7.11.11, cAMP-dependent protein kinase. Elongation factor 2 is phosphorylated in several cell types in response to various growth factors, hormones and other stimuli that raise intracellular Ca2+ [1,2].
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
Ca2+/calmodulin-dependent kinase III, Ca2+/calmodulin–dependent kinase III, calcium/calmodulin-dependent protein kinase III, eEF-2 kinase, EEF-2K, eEF2 kinase, eEF2-kinase, eEF2K, EF-2K, EF2K, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate
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